AMPK: guardian of metabolism and mitochondrial homeostasis

S Herzig, RJ Shaw - Nature reviews Molecular cell biology, 2018 - nature.com
Cells constantly adapt their metabolism to meet their energy needs and respond to nutrient
availability. Eukaryotes have evolved a very sophisticated system to sense low cellular ATP …

[HTML][HTML] AMPK in skeletal muscle function and metabolism

R Kjøbsted, JR Hingst, J Fentz, M Foretz… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …

AMPK, mitochondrial function, and cardiovascular disease

S Wu, MH Zou - International journal of molecular sciences, 2020 - mdpi.com
Adenosine monophosphate-activated protein kinase (AMPK) is in charge of numerous
catabolic and anabolic signaling pathways to sustain appropriate intracellular adenosine …

New strategies in sport nutrition to increase exercise performance

GL Close, DL Hamilton, A Philp, LM Burke… - Free radical biology and …, 2016 - Elsevier
Despite over 50 years of research, the field of sports nutrition continues to grow at a rapid
rate. Whilst the traditional research focus was one that centred on strategies to maximise …

The role of AMPK in the regulation of skeletal muscle size, hypertrophy, and regeneration

DM Thomson - International journal of molecular sciences, 2018 - mdpi.com
AMPK (5'-adenosine monophosphate-activated protein kinase) is heavily involved in
skeletal muscle metabolic control through its regulation of many downstream targets …

AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion

B Cunniff, AJ McKenzie, NH Heintz… - Molecular biology of the …, 2016 - Am Soc Cell Biol
Cell migration is a complex behavior involving many energy-expensive biochemical events
that iteratively alter cell shape and location. Mitochondria, the principal producers of cellular …

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity

L Lantier, J Fentz, R Mounier, J Leclerc… - The FASEB …, 2014 - Wiley Online Library
ABSTRACT AMP‐activated protein kinase (AMPK) is a sensor of cellular energy status that
plays a central role in skeletal muscle metabolism. We used skeletal muscle‐specific …

Expanding roles for AMPK in skeletal muscle plasticity

R Mounier, M Théret, L Lantier, M Foretz… - Trends in Endocrinology & …, 2015 - cell.com
Skeletal muscle possesses a remarkable plasticity and responds to environmental and
physiological challenges by changing its phenotype in terms of size, composition, and …

AMP-activated protein kinase controls exercise training-and AICAR-induced increases in SIRT3 and MnSOD

J Brandauer, MA Andersen, H Kellezi, S Risis… - Frontiers in …, 2015 - frontiersin.org
The mitochondrial protein deacetylase sirtuin (SIRT) 3 may mediate exercise training-
induced increases in mitochondrial biogenesis and improvements in reactive oxygen …

The role of AMPK in controlling metabolism and mitochondrial biogenesis during exercise

K Marcinko, GR Steinberg - Experimental physiology, 2014 - Wiley Online Library
New Findings What is the topic of this review? The topic of this review is the metabolic
effects of AMP‐activated protein kinase (AMPK) on glucose and fatty acid (FA) uptake, FA …