Gamma-hydroxybutyrate (GHB), 1, 4-butanediol (1, 4BD), and gamma-butyrolactone (GBL) intoxication: A state-of-the-art review
L Dufayet, S Bargel, A Bonnet, AK Boukerma… - Regulatory Toxicology …, 2023 - Elsevier
Abstract γ-hydroxybutyrate (GHB) is synthesized endogenously from γ-aminobutyric acid
(GABA) or exogenously from 1, 4-butanediol (butane-1, 4-diol; 1, 4-BD) or γ-butyrolactone …
(GABA) or exogenously from 1, 4-butanediol (butane-1, 4-diol; 1, 4-BD) or γ-butyrolactone …
Acide γ-Hydroxybutyrique (GHB), γ-butyrolactone (GBL) et 1, 4-butanediol (1, 4-BD): revue de la littérature des aspects pharmacologiques, cliniques, analytiques et …
L Dufayet, S Bargel, A Bonnet, AK Boukerma… - … Analytique et Clinique, 2023 - Elsevier
Introduction γ-hydroxybutyric acid (GHB) is produced endogenously from γ-aminobutyric
acid (GABA) or formed after the absorption of γ-butyrolactone (GBL) or 1, 4-butanediol (1, 4 …
acid (GABA) or formed after the absorption of γ-butyrolactone (GBL) or 1, 4-butanediol (1, 4 …
GHB related acids are useful in routine casework of suspected GHB intoxication cases
P Jarsiah, J Roehrich, T Kueting, W Martz… - Forensic Science …, 2021 - Elsevier
Abstract GHB related acids (3, 4-dihydroxy butyric acid, 2, 4-dihydroxy butyric acid and
glycolic acid) are produced through oxidative GHB metabolism. These analytes could be …
glycolic acid) are produced through oxidative GHB metabolism. These analytes could be …
New gamma‐hydroxybutyric acid (GHB) biomarkers: Development and validation of a liquid chromatography–tandem mass spectrometry method for the determination …
AE Steuer, L Sutter, C Steuer… - Drug Testing and …, 2023 - Wiley Online Library
Gamma‐hydroxybutyric acid (GHB) represents an important drug in clinical and forensic
toxicology, particularly in the context of drug‐facilitated crimes. Analytically, GHB remains a …
toxicology, particularly in the context of drug‐facilitated crimes. Analytically, GHB remains a …
[HTML][HTML] Complications in post-mortem GHB cut-off values in urine samples: A case report
NHC Loos, KE van den Hondel, UJL Reijnders… - Toxicology Reports, 2023 - Elsevier
Gamma-hydroxybutyric acid (GHB) is a drug of abuse, that interplays with a GABAergic
system, resulting in an euphoric state and increased mood and impulses. Two cases of fatal …
system, resulting in an euphoric state and increased mood and impulses. Two cases of fatal …
Urinary concentrations of GHB and its novel amino acid and carnitine conjugates following controlled GHB administration to humans
AE Steuer, F Bavato, LK Schnider, DA Dornbierer… - Scientific Reports, 2023 - nature.com
Gamma-hydroxybutyrate (GHB) remains a challenging clinical/forensic toxicology drug. Its
rapid elimination to endogenous levels mainly causes this. Especially in drug-facilitated …
rapid elimination to endogenous levels mainly causes this. Especially in drug-facilitated …
Bestimmung von Gamma‐Hydroxybuttersäure und Gamma‐Hydroxybuttersäure‐Metaboliten im Haar und deren forensische Bedeutung
A Nebel, G Hamscher, RB Dettmeyer - Lebensmittelchemie, 2023 - Wiley Online Library
Gamma‐Hydroxybuttersäure (GHB) steht aufgrund ihres endogenen Vorkommens im
menschlichen Körper und zugleich sedierender Eigenschaften bei gewollter oder …
menschlichen Körper und zugleich sedierender Eigenschaften bei gewollter oder …
Apport de l'électrophorèse capillaire de zone dans l'exploration étiologique des acidoses métaboliques
P Houzé, L Labat - Toxicologie Analytique et Clinique, 2021 - Elsevier
Résumé Une valeur de pH plasmatique inférieure à 7, 35 caractérise une acidose
respiratoire, métabolique ou mixte. L'exploration des acidoses métaboliques est souvent …
respiratoire, métabolique ou mixte. L'exploration des acidoses métaboliques est souvent …