The role of astrocytes in the nucleus tractus solitarii in maintaining central control of autonomic function

D Martinez, DD Kline - American Journal of Physiology …, 2021 - journals.physiology.org
The nucleus tractus solitarii (nTS) is the first central site for the termination and integration of
autonomic and respiratory sensory information. Sensory afferents terminating in the nTS as …

Glial modulation of energy balance: The dorsal vagal complex is no exception

JD Troadec, S Gaigé, M Barbot, B Lebrun… - International Journal of …, 2022 - mdpi.com
The avoidance of being overweight or obese is a daily challenge for a growing number of
people. The growing proportion of people suffering from a nutritional imbalance in many …

Chronic intermittent hypoxia enhances glycinergic inhibition in nucleus tractus solitarius

S Jia, N Rybalchenko, K Kunwar… - Journal of …, 2022 - journals.physiology.org
Chronic intermittent hypoxia (CIH), an animal model of sleep apnea, has been shown to
alter the activity of second-order chemoreceptor neurons in the caudal nucleus of the solitary …

Unilateral vagotomy alters astrocyte and microglial morphology in the nucleus tractus solitarii of the rat

GC Hofmann, EM Hasser… - American Journal of …, 2021 - journals.physiology.org
The nucleus tractus solitarii (nTS) is the initial site of integration of sensory information from
the cardiorespiratory system and contributes to reflex responses to hypoxia. Afferent fibers of …

Nucleus tractus solitarii is required for the development and maintenance of phrenic and sympathetic long-term facilitation after acute intermittent hypoxia

D Ostrowski, CM Heesch, DD Kline… - Frontiers in …, 2023 - frontiersin.org
Exposure to acute intermittent hypoxia (AIH) induces prolonged increases (long term
facilitation, LTF) in phrenic and sympathetic nerve activity (PhrNA, SNA) under basal …

Circadian disruptions and their role in the development of hypertension

R Crowthers, T Thi Mong Nguyen… - Frontiers in …, 2024 - frontiersin.org
Circadian fluctuations in physiological setpoints are determined by the suprachiasmatic
nucleus (SCN) which exerts control over many target structures within and beyond the …

Gamma-aminobutyric acid transporters in the nucleus tractus solitarii regulate inhibitory and excitatory synaptic currents that influence cardiorespiratory function

D Martinez, L Lima-Silveira, MP Matott… - Frontiers in …, 2022 - frontiersin.org
The brainstem nucleus tractus solitarii (nTS) processes and modulates the afferent arc of
critical peripheral cardiorespiratory reflexes. Sensory afferents release glutamate to initiate …

Mechanisms underlying neuroplasticity in the nucleus tractus solitarii following hindlimb unloading in rats

L Lima-Silveira, D Martinez, EM Hasser, DD Kline - Neuroscience, 2020 - Elsevier
Hindlimb unloading (HU) in rats induces cardiovascular deconditioning (CVD) analogous to
that observed in individuals exposed to microgravity or bed rest. Among other physiological …

Oxytocin and corticotropin‐releasing hormone exaggerate nucleus tractus solitarii neuronal and synaptic activity following chronic intermittent hypoxia

P Gama de Barcellos Filho, HA Dantzler… - The Journal of …, 2024 - Wiley Online Library
Chronic intermittent hypoxia (CIH) in rodents mimics the hypoxia‐induced elevation of blood
pressure seen in individuals experiencing episodic breathing. The brainstem nucleus tractus …

Vagotomy blunts cardiorespiratory responses to vagal afferent stimulation via pre‐and postsynaptic effects in the nucleus tractus solitarii

GC Hofmann, P Gama de Barcellos Filho… - The Journal of …, 2024 - Wiley Online Library
Viscerosensory information travels to the brain via vagal afferents, where it is first integrated
within the brainstem nucleus tractus solitarii (nTS), a critical contributor to cardiorespiratory …