Calcium phosphate (CaP)-based bioceramics are the most widely used synthetic
biomaterials for reconstructing damaged bone. Accompanied by bone healing process …

Bone tissue engineering holds great promise for the regeneration of damaged or severe
bone defects. However, several challenges hinder its translation into clinical practice. To …

Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …

Mesenchymal stem cells (MSCs) are a promising candidate for bone repair. However, the
maintenance of MSCs injected into the bone injury site remains inefficient. A potential …

Traditional bone replacement materials have been developed with the goal of directing the
osteogenesis of osteoblastic cell lines toward differentiation and therefore achieving …

Osteoblasts, cells derived from mesenchymal stem cells (MSCs) in the bone marrow, are
cells responsible for bone formation and remodeling. The differentiation of osteoblasts from …

Hydroxyapatite (HA) is a promising scaffold material for the treatment of bone defects.
However, the lack of angiogenic properties and undesirable mechanical properties (such as …

Three-dimensional printing technology with the rapid development of printing materials are
widely recognized as a promising way to fabricate bioartificial bone tissues. In consideration …

Hydroxyapatite (HA) is a biomaterial widely used to treat bone defect, such as due to traffic
accident. The HA scaffold is obtained from synthetic HA or natural sources, such as bovine …

Introduction: Hybrids consist of inorganic and organic co-networks that are indistinguishable
above the nanoscale, which can lead to unprecedented combinations of properties, such as …