The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …

Drug resistance has profoundly limited the success of cancer treatment, driving relapse,
metastasis, and mortality. Nearly all anticancer drugs and even novel immunotherapies …

Chimeric antigen receptor (CAR) T-cell therapy has shown promise in the treatment of
haematological cancers and is currently being investigated for solid tumours, including high …

Simple Summary CAR-T cell immunotherapy uses engineered T lymphocytes to recognize
cancer antigens and to directly attack cancer cells and have been successfully used against …

The main aim of this research work is to find the numerical solution based on a meshless
technique for both the time-dependent Cahn–Hilliard and tumor growth partial differential …

Contracting cancer typically induces a state of terror among the individuals who are affected.
Exploring how chemotherapy and anxiety work together to affect the speed at which cancer …

We develop a mathematical model to examine the role of helper and cytotoxic T cells in an
anti-tumour immune response. The model comprises three ordinary differential equations …

Simple Summary Osteosarcoma is the most common primary bone tumor and has a poor
prognosis. Therefore, it is important to understand the mechanism of the development of …

Simple Summary Osteosarcoma is a rare type of cancer with poor prognoses. However, to
the best of our knowledge, there are no mathematical models that study the impact of …

Sustained-release delivery systems, such as hydrogels, significantly improve cancer
therapies by extending the treatment efficacy and avoiding excess wash-out. Combined …