Covering: Up to January 2020 Meroterpenoids derived from the polyketide 1, 3, 6, 8- tetrahydroxynaphthalene (THN) are complex natural products produced exclusively by …
JH George - Accounts of Chemical Research, 2021 - ACS Publications
Conspectus Natural products are biosynthesized from a limited pool of starting materials via pathways that obey the same chemical logic as textbook organic reactions. Given the …
BRK Menon, D Richmond, N Menon - Catalysis Reviews, 2022 - Taylor & Francis
Nature's repertoire of bio-halogenase enzymes is intriguing with halogenases from various natural product biosynthetic clusters that carry out site and region-specific halogenation of …
Y Ji, B Hong, I Franzoni, M Wang… - Angewandte Chemie …, 2022 - Wiley Online Library
Capitalizing on the late‐stage diversification of an essential 1, 3‐diene intermediate, we describe herein a 9‐step enantioselective total synthesis of (+)‐hyperforin and (+) …
S Fu, B Liu - Organic Chemistry Frontiers, 2020 - pubs.rsc.org
Limonoid and limonoid-like natural products have demonstrated diverse bioactive properties and attracted considerable synthetic efforts. They provide a good platform to examine the …
Y Zhou, L Wang, G Yuan, S Liu, X Sun, C Yuan… - Organic …, 2020 - ACS Publications
The first catalytic asymmetric Kumada cross-coupling of organic halides with alkenyl Grignard reagents has been developed. The reaction was promoted by the cobalt …
Total synthesis of the Rhododendron meroterpenoids rubiginosins A and G, which both contain unusual 6–6–6–4 ring systems, has been achieved using a bioinspired cascade …
The stunning advances in understanding the reactivity and selectivity principles of asymmetric pericyclic reactions have had a profound impact on the synthetic planning of …
L Gurgone, A La-Venia, D Caprioglio… - Frontiers in Natural …, 2023 - frontiersin.org
The chemistry of phytocannabinoids has witnessed renewed interest these last decades as a consequence of reduced restrictions, research on the endocannabinoid system and the …