Biological roles of fibroblast growth factor-2

A Bikfalvi, S Klein, G Pintucci, DB Rifkin - Endocrine reviews, 1997 - academic.oup.com
Biological Roles of Fibroblast Growth Factor-2* | Endocrine Reviews | Oxford Academic
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Fibroblast growth factors as angiogenesis factors: new insights into their mechanism of action

S Klein, M Roghani, DB Rifkin - Regulation of angiogenesis, 1997 - Springer
Angiogenesis is critical for physiological processes such as embryonic development and
wound repair (D'Amore and Thompson, 1987; Folkman and Shing, 1992). Angiogenesis …

Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice.

JD Coffin, RZ Florkiewicz, J Neumann… - Molecular biology of …, 1995 - Am Soc Cell Biol
Basic fibroblast growth factor (FGF-2) is a pleiotropic growth factor detected in many different
cells and tissues. Normally synthesized at low levels, FGF-2 is elevated in various …

Nuclear activities of basic fibroblast growth factor: potentiation of low-serum growth mediated by natural or chimeric nuclear localization signals

M Arese, Y Chen, RZ Florkiewicz… - Molecular biology of …, 1999 - Am Soc Cell Biol
Human basic fibroblast growth factor (FGF-2) occurs in four isoforms: a low molecular weight
(LMW FGF-2, 18 kDa) and three high molecular weight (HMW FGF-2, 22, 22.5, and 24 kDa) …

Stanniocalcin 1 and 2 are secreted as phosphoproteins from human fibrosarcoma cells

DA JELLINEK, AC CHANG, MR LARSEN… - Biochemical …, 2000 - portlandpress.com
Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are two recently identified mammalian
peptide hormones. STC1 plays a role in calcium and phosphate homoeostasis, while the …

Ecto-protein kinases: ecto-domain phosphorylation as a novel target for pharmacological manipulation?

FA Redegeld, CC Caldwell, MV Sitkovsky - Trends in pharmacological …, 1999 - cell.com
An increasing number of studies document the presence of protein kinases facing outwards
at the cell surface of a diverse array of cells. These ecto-protein kinases phosphorylate cell …

Proteins in unexpected locations.

NR Smalheiser - Molecular biology of the cell, 1996 - Am Soc Cell Biol
Members of all classes of proteins--cytoskeletal components, secreted growth factors,
glycolytic enzymes, kinases, transcription factors, chaperones, transmembrane proteins, and …

Evidence for cAMP-dependent platelet ectoprotein kinase activity that phosphorylates platelet glycoprotein IV (CD36)

M Hatmi, JM Gavaret, I Elalamy, BB Vargaftig… - Journal of Biological …, 1996 - ASBMB
The dephosphorylating enzyme alkaline phosphatase, by removing phosphate groups from
the external platelet membrane proteins, modulates platelet activation (Hatmi, M., Haye, B …

Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution.

G Pintucci, N Quarto, DB Rifkin - Molecular biology of the cell, 1996 - Am Soc Cell Biol
The high molecular weight (HMW) forms (24, 22.5, and 22 kDa) of basic fibroblast growth
factor-2 (FGF-2) contain an N-terminal extension responsible for their predominantly nuclear …

[HTML][HTML] Inhibition of the tyrosine kinase activity of the fibroblast growth factor receptor by the methyltransferase inhibitor 5'-methylthioadenosine.

PA Maher - Journal of Biological Chemistry, 1993 - Elsevier
Stimulation of fibroblasts with basic fibroblast growth factor (bFGF) led to the rapid tyrosine
phosphorylation of a number of cellular proteins, including a major substrate of 90 kDa. The …