Arachidonic acid (AA), an n‐6 essential fatty acid, is a major component of mammalian cells
and can be released by phospholipase A2. Accumulating evidence indicates that AA plays …

Cytochrome P450 (CYP450) is a group of enzymes that play an essential role in Phase I
metabolism, with 57 functional genes classified into 18 families in the human genome, of …

Lipids are important in multiple cellular functions, with most having structural or energy
storage roles. However, a small fraction of lipids exert bioactive roles through binding to G …

Even after decades of research, the mechanism of neurodegeneration remains
understudied, hindering the discovery of effective treatments for neurodegenerative …

Liver cancer is a malignancy developed from underlying liver disease that encompasses
liver injury and metabolic disorders. The progression from these underlying liver disease to …

Due to the aging population in the world, neurodegenerative diseases have become a
serious public health issue that greatly impacts patients' quality of life and adds a huge …

Liver fibrosis is a common outcome of most chronic liver insults/injuries that can develop into
an irreversible process of cirrhosis and, eventually, liver cancer. In recent years, there has …

Vitamin E acts as essential antioxidant against detrimental oxidation of biological molecules
induced by multiple reactive species. To gain more insight into the physiological role of …

Age-associated changes leading to a decline in cardiac structure and function contribute to
the increased susceptibility and incidence of cardiovascular diseases (CVD) in elderly …

Lipids are organic compounds insoluble in water with a variety of metabolic and non-
metabolic functions. They not only represent an efficient energy substrate but can also act as …