The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

The regular overconsumption of energy‐dense foods (rich in lipids and sugars) results in
elevated intestinal nutrient absorption and consequently excessive accumulation of lipids in …

Fatty acid–binding proteins (FABPs) are small lipid-binding proteins abundantly expressed
in tissues that are highly active in fatty acid (FA) metabolism. Ten mammalian FABPs have …

The endocannabinoids 2‐arachidonoylglycerol (2‐AG) and anandamide are among the
best studied lipid messengers in the brain. By activating cannabinoid receptors in the CNS …

The family of intracellular lipid binding proteins (iLBPs) is comprised of 16 members of
structurally related binding proteins that have ubiquitous tissue expression in humans. iLBPs …

Abstract Retinol-binding protein 2 (RBP2; originally cellular retinol-binding protein, type II
(CRBPII)) is a 16 kDa cytosolic protein that in the adult is localized predominantly to …

There are significant sex differences in colorectal cancer (CRC), including in incidence,
onset, and molecular characteristics. Further, while inflammatory bowel disease (IBD) is a …

Background Retinol-binding protein 2 (RBP2) is an intracellular carrier for vitamin A in the
absorptive enterocytes. Mice lacking RBP2 (Rbp2−/−) display an unexpected phenotype of …

We developed an innovative millifluidic organ-on-a-chip device, named MINERVA 2.0, that
is optically accessible and suitable to serial connection. In the present work, we evaluated …

Evaluating chemicals for potential in vivo toxicity based on their in vitro bioactivity profile is
an important step toward animal-free testing. A compendium of reference chemicals and …