During the last decades, the pleiotropic antitumor functions exerted by type I interferons
(IFNs) have become universally acknowledged, especially their role in mediating …

Simple Summary The treatment of cancer has progressed greatly with the advent of
immunotherapy and gene therapy, including the use of nonreplicating adenoviral vectors to …

Melanoma is a prevalent, aggressive form of cancer in dogs. New treatment or preventive
modalities are necessary to control this disease in dogs. On December 03, 2020, the …

Malignant melanoma is a type of cancer with high death rates due, in part, to the lack of
efficient treatments once metastases have formed. 1 The tumor suppressor protein p53 is …

Abstract Interferon-β (IFN-β) exhibits a tumor-killing effect; however, injection of IFN-β alone
for lung cancer is often accompanied by side effects. This study investigated the possibility of …

Therapeutic strategies that act by eliciting and enhancing antitumor immunity have been
clinically validated as an effective treatment modality but may benefit from the induction of …

Balancing safety and efficacy is a major consideration for cancer treatments, especially
when combining cancer immunotherapy with other treatment modalities such as …

Immune evasion is an important cancer hallmark and the understanding of its mechanisms
has generated successful therapeutic approaches. Induction of immunogenic cell death …

Alternative treatments for cancer using gene therapy approaches have shown promising
results and some have even reached the marketplace. Even so, additional improvements …

Melanoma is the deadliest type of skin cancer with steadily increasing incidence worldwide
during the last few decades. In addition to its tumor associated antigens (TAAs), melanoma …