Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

Growing tumors acquire the ability to resist immune recognition and immune-mediated
injury. Among several mechanisms, mouse and human tumors share the ability to alter the …

Tumor growth is associated with the accumulation of immature myeloid cells (ImC), which in
mice are characterized by the expression of Gr-1 and CD11b markers. These cells suppress …

Transformed cells of cancers may be related to stromal cells, immune cells, and some
bacteria such as Fusobacterium nucleatum. This review aimed to evaluate carcinogenesis …

Immunotherapy may provide valid alternative therapy for patients with hormone-refractory
metastatic prostate cancer. However, if the tumor environment exerts a suppressive action …

The naturally occurring polycationic polyamines including putrescine, spermidine, and
spermine play an important role in cell growth, differentiation, and gene expression …

Fusobacterium nucleatum (F. nucleatum) is one of the most abundant Gram-negative
anaerobic bacteria, part of the gut, and oral commensal flora, generally found in human …

Owing to the establishment of cells and transgenic animals which either lack or over-express
acetylCoA: spermidine N 1-acetyltransferase a major progress was made in our …

Metabolism of polyamines spermidine and spermine, and their diamine precursor,
putrescine, has been a target for antineoplastic therapy since these naturally occurring alkyl …

Background: The disturbances leading to cancer cachexia remain to be unraveled.
Preliminary evidence suggests that arginine availability in cancer is reduced. However, no …