Stem cells are distinctive cells that have self-renewal potential and unique ability to
differentiate into multiple functional cells. Stem cell is a frontier field of life science research …

Phenotypes are driven by regulated gene expression, which in turn are mediated by
complex interactions between diverse biological molecules. Protein–DNA interactions such …

The cells of the intestinal epithelium establish the frontline for host defense against
pathogens in the gastrointestinal tract and play a vital role in the initiation of the immune …

Background Microglia are resident immunocompetent and phagocytic cells in the CNS. Pro-
inflammatory microglia, stimulated by microbial signals such as bacterial lipopolysaccharide …

The expression of inducible nitric oxide synthase (iNOS; NOS2) and derived NO in various
cancers was reported to exert pro-and anti-tumorigenic effects depending on the levels of …

Long non-coding RNAs (lncRNAs) are significant contributors in maintaining genomic
integrity through epigenetic regulation. LncRNAs can interact with chromatin-modifying …

Ferroptosis is an iron-dependent form of cell death, which is reported to be associated with
glioma progression and drug sensitivity. Targeting ferroptosis is a potential therapeutic …

Self-renewal and differentiation into diverse cells are two main characteristics of stem cells.
These cells have important roles in development and homeostasis of different tissues and …

LncRNA (long non-coding RNA)-protein interaction (LPI) has effects on chromosome
structure and gene transcription, participating in key cellular processes such as signal …

Mammalian genomic DNA is packed in a small nucleus, and its folding and organization in
the nucleus are critical for gene regulation and cell fate determination. In interphase …