Dural immune cells, CGRP, and migraine

LK Balcziak, AF Russo - Frontiers in neurology, 2022 - frontiersin.org
Migraine is the most common neurological disorder in the world, affecting 12% of the
population. Migraine involves the central nervous system, trigeminal nerves and meninges …

[HTML][HTML] Pretreatment inflammatory markers predicting treatment outcomes in colorectal cancer

S An, H Shim, K Kim, B Kim, HJ Bang, H Do… - Annals of …, 2022 - ncbi.nlm.nih.gov
We aimed to review whether pretreatment inflammatory markers reflect the short-and long-
term outcomes of patients with colon cancer, rectal cancer, colon and rectal cancers, and …

Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod …

NO Al-Harbi, SF Ahmad, M Almutairi, AZ Alanazi… - Cellular …, 2022 - Elsevier
Psoriasis is a chronic dermal inflammatory disease with a world-wide prevalence in which
different immune/non-immune cells, eg T cells, macrophages, neutrophils, and keratinocytes …

[HTML][HTML] Raman-based spectrophenotyping of the most important cells of the immune system

A Borek-Dorosz, AM Nowakowska… - Journal of Advanced …, 2022 - Elsevier
Introduction Human peripheral blood mononuclear cells (PBMCs) are a heterogeneous
population of cells that includes T and B lymphocytes. The total number of lymphocytes and …

Modulation of the tumor microenvironment by natural agents: implications for cancer prevention and therapy

H Zubair, MA Khan, S Anand, SK Srivastava… - Seminars in cancer …, 2022 - Elsevier
The development of cancer is not just the growth and proliferation of a single transformed
cell, but its surrounding environment also coevolves with it. Indeed, successful cancer …

Peripheral blood classical monocytes and plasma interleukin 10 are associated to neoadjuvant chemotherapy response in breast cancer patients

J Valdés-Ferrada, N Muñoz-Durango… - Frontiers in …, 2020 - frontiersin.org
Worldwide, breast cancer (BC) is the leading cause of cancer death among women. For
many patients the most effective treatment is a resection surgery that removes the tumor …

IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model

C Cardinez, Y Hao, K Kwong, AR Davies… - Nature …, 2024 - nature.com
Loss-of-function mutations have provided crucial insights into the immunoregulatory actions
of Foxp3+ regulatory T cells (Tregs). By contrast, we know very little about the consequences …

[HTML][HTML] Transcriptome profiling of microdissected cortex and medulla unravels functional regionalization in the European sea bass Dicentrarchus labrax thymus

A Miccoli, V Pianese, C Bidoli, AM Fausto… - Fish & Shellfish …, 2024 - Elsevier
The thymus is a sophisticated primary lymphoid organ in jawed vertebrates, but knowledge
on teleost thymus remains scarce. In this study, for the first time in the European sea bass …

Oral administration of procyanidin B2 3, 3"-di-O-gallate ameliorates experimental autoimmune encephalomyelitis through immunosuppressive effects on CD4+ T cells …

K Endo, T Sawa, Y Tanaka, T Saiki, H Haga… - European Journal of …, 2023 - Elsevier
Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system
caused by the excessive activation of T cells. Procyanidins are polyphenols that exhibit anti …

Simulated microgravity disrupts nuclear factor κb signaling and impairs murine dendritic cell phenotype and function

G Calcagno, J Jeandel, JP Frippiat… - International Journal of …, 2023 - mdpi.com
During spaceflights, astronauts face different forms of stress (eg, socio-environmental and
gravity stresses) that impact physiological functions and particularly the immune system. In …