Bronchiectasis: new therapies and new perspectives

JD Chalmers, SH Chotirmall - The lancet Respiratory medicine, 2018 - thelancet.com
Summary European Respiratory Society guidelines for the management of adult
bronchiectasis highlight the paucity of treatment options available for patients with this …

Targeting to macrophages: role of physicochemical properties of particulate carriers—liposomes and microspheres—on the phagocytosis by macrophages

F Ahsan, IP Rivas, MA Khan, AIT Suárez - Journal of controlled release, 2002 - Elsevier
Heterogeneous functions of macrophages in human immune systems have renewed interest
in targeting of drugs to these cells. Various carrier systems have emerged to deliver drugs to …

Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor

JO Armitage - Blood, The Journal of the American Society of …, 1998 - ashpublications.org
CLINICAL INDICATIONS for use of recombinant human granulocyte-macrophage colony-
stimulating factor (rHuGM-CSF) have expanded considerably since the drug first became …

Causation of Crohn's Disease by Mycobacterium avium Subspecies Paratuberculosis

J Hermon-Taylor, TJ Bull, JM Sheridan… - Canadian Journal of …, 2000 - Wiley Online Library
Mycobacterium avium subspecies paratuberculosis (MAP) is a member of the M avium
complex (MAC). It differs genetically from other MAC in having 14 to 18 copies of IS900 and …

Biodegradable nanoparticles for intracellular delivery of antimicrobial agents

S Xie, Y Tao, Y Pan, W Qu, G Cheng, L Huang… - Journal of Controlled …, 2014 - Elsevier
Biodegradable nanoparticles have emerged as a promising strategy for ferrying
antimicrobial agents into specific cells due to their unique properties. This review discusses …

[HTML][HTML] Demonstration of a fusion mechanism between a fluid bactericidal liposomal formulation and bacterial cells

S Sachetelli, H Khalil, T Chen, C Beaulac… - … et Biophysica Acta (BBA …, 2000 - Elsevier
It was previously demonstrated that fluid liposomal-encapsulated tobramycin, named
Fluidosomes, was successful in eradicating mucoid Pseudomonas aeruginosa in an animal …

In-vitro bactericidal efficacy of sub-MIC concentrations of liposome-encapsulated antibiotic against gram-negative and gram-positive bacteria.

C Beaulac, S Sachetelli, J Lagace - The Journal of antimicrobial …, 1998 - academic.oup.com
It has been shown previously that tobramycin encapsulated in fluid liposomes (composed of
dipalmitoylphosphatidylcholine (DPPC) and dimyristoylphosphatidylglycerol (DMPG)) …

Two-year-outcomes analysis of Crohn's disease treated with rifabutin and macrolide antibiotics.

GP Gui, PR Thomas, ML Tizard, J Lake… - The Journal of …, 1997 - academic.oup.com
Fifty-two patients with severe Crohn's disease were enrolled in this study. Six (11.5%) were
intolerant of the medication and had to be excluded. The remaining 46 patients were treated …

Treatment of severe Crohn's disease using antimycobacterial triple therapy—approaching a cure?

TJ Borody, S Leis, EF Warren, R Surace - Digestive and Liver Disease, 2002 - Elsevier
Background. Mycobacterium avium subspecies paratuberculosis is probably the best
candidate for a microbial cause of Crohn's disease although arguments to the contrary can …

The challenges and applications of nanotechnology against bacterial resistance

Z Lei, A Karim - Journal of Veterinary Pharmacology and …, 2021 - Wiley Online Library
Bacterial resistance to the antibiotics develops rapidly and is increasingly serious health
concern in the world. It is an insoluble topic due to the multiple resistant mechanisms. The …