During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

The establishment of a functional placenta is pivotal for normal fetal development and the
maintenance of pregnancy. In the course of early placentation, trophoblast precursors …

Organismal function is, to a great extent, determined by interactions among their
fundamental building blocks, the cells. In this work, we studied the cell-cell interactome of …

Development of the human placenta and its different epithelial trophoblasts is crucial for a
successful pregnancy. Besides fusing into a multinuclear syncytium, the exchange surface …

Normal pregnancy (NP) involves intricate processes starting with egg fertilization,
proceeding to embryo implantation, placentation and gestation, and culminating in …

Introduction Research on human placental development and function lacks a conclusive in
vivo model. To investigate the intracellular molecular mechanisms in trophoblast cells …

Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many
processes required for a successful pregnancy. Over the past decades, increasing evidence …

Uterine spiral arteries are extensively remodeled during placentation to ensure sufficient
delivery of maternal blood to the developing fetus. Uterine spiral arterial remodeling is …

Preeclampsia is a multi-organ complication of pregnancy characterized by sudden
hypertension and proteinuria that is among the leading causes of preterm delivery and …

Background Mapping of allele-specific DNA methylation (ASM) can be a post-GWAS
strategy for localizing regulatory sequence polymorphisms (rSNPs). The advantages of this …