Beyond the brain: peripheral interactions after traumatic brain injury

SJ McDonald, JM Sharkey, M Sun… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of death and disability, and there are currently
no pharmacological treatments known to improve patient outcomes. Unquestionably …

The role of the microbiota–gut–brain axis in long‐term neurodegenerative processes following traumatic brain injury

LS Chiu, RS Anderton - European Journal of Neuroscience, 2023 - Wiley Online Library
Traumatic brain injury (TBI) can be a devastating and debilitating disease to endure. Due to
improvements in clinical practice, declining mortality rates have led to research into the long …

Muscle atrophy in mechanically-ventilated critically ill children

RW Johnson, KWP Ng, AR Dietz, ME Hartman… - PLoS …, 2018 - journals.plos.org
Importance ICU-acquired muscle atrophy occurs commonly and worsens outcomes in
adults. The incidence and severity of muscle atrophy in critically ill children are poorly …

Making sense of gut feelings in the traumatic brain injury pathogenesis

LFF Royes, F Gomez-Pinilla - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Traumatic brain injury (TBI) is a devastating condition which often initiates a sequel of
neurological disorders that can last throughout lifespan. From metabolic perspective, TBI …

[HTML][HTML] Sustained local ionic homeostatic imbalance caused by calcification modulates inflammation to trigger heterotopic ossification

M Bohner, Y Maazouz, MP Ginebra, P Habibovic… - Acta Biomaterialia, 2022 - Elsevier
Heterotopic ossification (HO) is a condition triggered by an injury leading to the formation of
mature lamellar bone in extraskeletal soft tissues. Despite being a frequent complication of …

Lespedeza bicolor extract supplementation reduced hyperglycemia-induced skeletal muscle damage by regulation of AMPK/SIRT/PGC1α–related energy metabolism …

H Lee, SY Kim, Y Lim - Nutrition Research, 2023 - Elsevier
Lespedeza bicolor (LB) is known to have antidiabetic activities; however, the underlying
molecular mechanisms of LB in hyperglycemia-induced skeletal muscle damage is unclear …

Models of traumatic brain injury in aged animals: a clinical perspective

A Iboaya, JL Harris, AN Arickx… - … and neural repair, 2019 - journals.sagepub.com
Traumatic brain injury (TBI) is a major cause of morbidity and mortality in the United States,
with advanced age being one of the major predictors of poor prognosis. To replicate the …

Paraspinal muscle morphology and composition in adolescent idiopathic scoliosis: A histological analysis

B Shahidi, A Yoo, C Farnsworth, PO Newton… - JOR …, 2021 - Wiley Online Library
Background Adolescent idiopathic scoliosis (AIS) is a condition resulting in spinal deformity
and tissue adaptation of the paraspinal muscles. Although prior studies have demonstrated …

Nandrolone Abuse Prior to Head Trauma Mitigates Endoplasmic Reticulum Stress, Mitochondrial Bioenergetic Deficits, and Markers of Neurodegeneration

MS Rodolphi, NR Strogulski, A Kopczynski… - Molecular …, 2024 - Springer
The abuse of synthetic steroids, such as nandrolone decanoate (ND), is often associated
with violent behavior, increasing the risk of traumatic brain injury (TBI). After a TBI, proteins …

[HTML][HTML] Modelling physical resilience in ageing mice

M Schosserer, G Banks, S Dogan, P Dungel… - Mechanisms of ageing …, 2019 - Elsevier
Geroprotectors, a class of drugs targeting multiple deficits occurring with age, necessitate
the development of new animal models to test their efficacy. The COST Action MouseAGE is …