The life and times of a tRNA

EM Phizicky, AK Hopper - RNA, 2023 - rnajournal.cshlp.org
The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …

Signaling to and from the RNA polymerase III transcription and processing machinery

IM Willis, RD Moir - Annual review of biochemistry, 2018 - annualreviews.org
RNA polymerase (Pol) III has a specialized role in transcribing the most abundant RNAs in
eukaryotic cells, transfer RNAs (tRNAs), along with other ubiquitous small noncoding RNAs …

Regulation of tRNA synthesis by the general transcription factors of RNA polymerase III-TFIIIB and TFIIIC, and by the MAF1 protein

D Graczyk, M Cieśla, M Boguta - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
The synthesis of transfer RNA (tRNA) is directed by RNA polymerase III (Pol III) specialized
in high-level transcription of short DNA templates. Pol III recruitment to tRNA genes is …

A tRNA's fate is decided at its 3′ end: Collaborative actions of CCA-adding enzyme and RNases involved in tRNA processing and degradation

K Wellner, H Betat, M Mörl - Biochimica et Biophysica Acta (BBA)-Gene …, 2018 - Elsevier
Abstract tRNAs are key players in translation and are additionally involved in a wide range
of distinct cellular processes. The vital importance of tRNAs becomes evident in numerous …

Maf1 phosphorylation is regulated through the action of prefoldin-like Bud27 on PP4 phosphatase in Saccharomyces cerevisiae

F Gutiérrez-Santiago… - Nucleic Acids …, 2024 - academic.oup.com
Bud27 is a prefoldin-like protein that participates in transcriptional regulation mediated by
the three RNA polymerases in Saccharomyces cerevisiae. Lack of Bud27 significantly …

[HTML][HTML] Maf1 ameliorates cardiac hypertrophy by inhibiting RNA polymerase III through ERK1/2

Y Sun, C Chen, R Xue, Y Wang, B Dong, J Li… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: An imbalance between protein synthesis and degradation is one of the
mechanisms of cardiac hypertrophy. Increased transcription in cardiomyocytes can lead to …

Interactions between RNAP III transcription machinery and tRNA processing factors

GA Arimbasseri - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2018 - Elsevier
Eukaryotes have at least three nuclear RNA polymerases to carry out transcription. While
RNA polymerases I and II are responsible for ribosomal RNA transcription and messenger …

Host adaptation of Plasmodium falciparum translational control

Q Li - 2025 - openarchive.ki.se
Malaria, caused by the intracellular protozoan parasite Plasmodium falciparum, continues to
be a significant global health challenge. One of the major difficulties in combating the …

[图书][B] Similarities and Differences in tRNA Quality Control Decay Pathways in Evolutionarily Distant Yeast Species

T De Zoysa - 2021 - search.proquest.com
Abstract tRNAs are a critical component of translation and subject to numerous post
transcriptional modifications. Many tRNA modifications are conserved in eukaryotes and …