The nucleoside inosine plays an important role in purine biosynthesis, gene translation, and
modulation of the fate of RNAs. The editing of adenosine to inosine is a widespread post …

Transfer RNAs (tRNAs) are key players of protein synthesis, as they decode the genetic
information organized in mRNA codons, translating them into the code of 20 amino acids. To …

The alphabet of building blocks for RNA molecules is much larger than the standard four
nucleotides. The diversity is achieved by the post-transcriptional biochemical modification of …

CRISPR/Cas9‐guided cytidine deaminase enables C: G to T: A base editing in bacterial
genome without introduction of lethal double‐stranded DNA break, supplement of foreign …

Highlights•RNA can be modified by diverse internal and terminal modifications.•Bacteria and
bacteriophage RNA polymerases can install RNA modifications.•Bacterial enzymes remove …

By linking amino acids to their codon assignments, transfer RNAs (tRNAs) are essential for
protein synthesis and translation fidelity. Some human tRNA variants cause amino acid mis …

Transfer RNA (tRNA) molecules are sumptuously decorated with evolutionary conserved
post-transcriptional nucleoside modifications that are essential for structural stability and …

A-to-I RNA editing is a very important post-transcriptional modification or co-transcriptional
modification that creates isoforms and increases the diversity of proteins. In this process …

Rhodophyta are among the closest known relatives of green plants. Studying the codons of
their genomes can help us understand the codon usage pattern and characteristics of the …

A remarkable number of neurodevelopmental disorders have been linked to defects in tRNA
modifications. These discoveries place tRNA modifications in the spotlight as critical …