Abstract Process Analytical Technology (PAT) instruments include analyzers capable of
measuring physical and chemical process parameters and key attributes with the goal of …

Although hundreds of different adjuvants have been tried, aluminum-containing adjuvants
are by far the most widely used currently. It is worth mentioning that although aluminum …

Hydroxyapatite (HAP) has been formulated as adjuvants in vaccines for human use.
However, the optimal properties required for HAP nanoparticles to elicit adjuvanticity and the …

Diphtheria toxoid is produced by detoxification of diphtheria toxin with formaldehyde. This
study was performed to elucidate the chemical nature and location of formaldehyde-induced …

Purpose Aluminum-based adjuvants including aluminum phosphate (AlPO 4) are commonly
used in many human vaccines to enhance immune response. The interaction between the …

Introducing new recombinant protein antigens to existing pediatric combination vaccines is
important in improving coverage and affordability, especially in low-and middle-income …

The focus of this study was to examine the small-scale adsorption process of Tetanus Toxoid
(TT) as a model protein antigen to aluminum phosphate (AlPO 4) and aluminum …

Purpose A comparative assessment was performed to evaluate the potential of particle
sizing by an ensemble based conventional dynamic light scattering (DLS) technique and an …

Purpose The goal of this study was to characterize an acellular pertussis vaccine (Tdap)
containing genetically modified pertussis toxin (gdPT) and TLR agonist adsorbed to AlOOH …

Purpose This study is focused on monitoring process parameters and quality attributes of
aluminum phosphate (AlPO4) using multiple in-line probes incorporated into an industrial …