In this review, an attempt has been made to throw light on the mechanism of action of
colchicine and its different analogs as anti‐cancer agents. Colchicine interacts with tubulin …

In eukaryotic cells, microtubules, actin, and intermediate filaments interact to form the
cytoskeletal network involved in determination of cell architecture, intracellular transport …

Five β‐tubulin isotypes are expressed differentially during chicken brain development. One
of these isotypes is encoded by the gene cβ4 and has been assigned to an isotypic family …

Tau is a developmentally regulated microtubule-associated protein that influences
microtubule behavior by directly associating with tubulin. The carboxyl terminus of tau …

The growing and shortening dynamics of individual bovine brain microtubules at their plus
ends at steady state in vitro, assembled from isotypically pure alpha beta II, alpha beta III, or …

An acetylation site of Chlamydomonas axonemal alpha-tubulins was identified near, or
within, the binding site of 6-11B-1, a monoclonal antibody specific for posttranslationally …

Colchicine exerts its biological effects through binding to the soluble tubulin heterodimer, the
major component of the microtubule. The colchicine binding abilities of tubulins from a …

Tubulin proteins, as components of the microtubule cytoskeleton perform critical cellular
functions throughout all phases of the cell cycle. Altered tubulin isotype composition of …

A posttranslational modification was detected in the carboxyl-terminal region of axonemal
tubulin from Paramecium. Tubulin carboxyl-terminal peptides were isolated and analyzed by …

Class III beta-tubulin, isolated from adult bovine brain, is resolved into at least seven charge
variants on isoelectric focusing gels. To identify the posttranslational modifications …