Cell-free DNA (cfDNA) analysis represents a promising method for the diagnosis, treatment
selection and clinical follow-up of cancer patients. Although its general methodological …

Effective screening modalities are currently available for only a small subset of cancers, and
they generally have suboptimal performance with complicated procedures. Therefore, there …

Background A multi-cancer early detection (MCED) test used to complement existing
screening could increase the number of cancers detected through population screening …

Background Early cancer detection could identify tumors at a time when outcomes are
superior and treatment is less morbid. This prospective case-control sub-study (from …

Liquid biopsies hold the potential to inform cancer patient prognosis and to guide treatment
decisions at the time when direct tumor biopsy may be impractical due to its invasive nature …

Background: New technologies are being developed for early detection of multiple types of
cancer simultaneously. To quantify the potential benefit, we estimated reductions in absolute …

Acknowledging the increasing number of studies describing the use of whole-body MRI for
cancer screening, and the increasing number of examinations being performed in patients …

Aim Lung cancer screening reduces mortality. We aim to validate the performance of Lung
EpiCheck, a six-marker panel methylation-based plasma test, in the detection of lung cancer …

Advances in genomic strategies and the development of targeted therapies have enabled
precision medicine to revolutionise the field of oncology. Precision medicine uses patient …

Background: Multi-cancer tests offer screening for multiple cancers with one blood draw, but
the potential population impact is poorly understood. Methods: We formulate mathematical …