Tumor angiogenesis: molecular pathways and therapeutic targets

SM Weis, DA Cheresh - Nature medicine, 2011 - nature.com
As angiogenesis is essential for tumor growth and metastasis, controlling tumor-associated
angiogenesis is a promising tactic in limiting cancer progression. The tumor …

microRNAs (miRNAs) in glioblastoma multiforme (GBM)—recent literature review

M Makowska, B Smolarz, H Romanowicz - International Journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary
brain tumor. GBM is characterized by an infiltrating growth nature, abundant vascularization …

Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer

W Kong, L He, EJ Richards, S Challa, CX Xu… - Oncogene, 2014 - nature.com
Abstract MicroRNA-155 (miR-155) is frequently upregulated in various types of human
cancer; however, its role in cancer angiogenesis remains unknown. Here, we demonstrate …

MicroRNAs in human placental development and pregnancy complications

G Fu, J Brkić, H Hayder, C Peng - International journal of molecular …, 2013 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs, which function as critical
posttranscriptional regulators of gene expression by promoting mRNA degradation and …

[HTML][HTML] Circular RNAs in cancer: limitations in functional studies and diagnostic potential

F Li, Q Yang, AT He, BB Yang - Seminars in cancer biology, 2021 - Elsevier
Circular RNAs (circRNAs) are a large class of noncoding RNAs, generated from a process
called back-splicing, that possess critical regulatory functions in many cellular events. A …

A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion

HG Møller, AP Rasmussen, HH Andersen… - Molecular …, 2013 - Springer
Glioblastoma multiforme (GBM) is an incurable form of brain cancer with a very poor
prognosis. Because of its highly invasive nature, it is impossible to remove all tumor cells …

The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast …

AL Smith, R Iwanaga, DJ Drasin, DS Micalizzi… - Oncogene, 2012 - nature.com
The role of TGF-β signaling in tumorigenesis is paradoxical: it can be tumor suppressive or
tumor promotional, depending on context. The metastatic regulator, Six1, was recently …

MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer

N Li, Y Miao, Y Shan, B Liu, Y Li, L Zhao, L Jia - Cell death & disease, 2017 - nature.com
Accumulating evidences have revealed that dysregulated microRNAs (miRNAs) involve in
the tumorigenesis, progression and even lead to poor prognosis of various carcinomas …

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

Circulating microRNAs in patients with active pulmonary tuberculosis

Y Fu, Z Yi, X Wu, J Li, F Xu - Journal of clinical microbiology, 2011 - Am Soc Microbiol
Emerging evidence shows that microRNAs (miRNAs) play an important role in pathogen-
host interactions. Circulating miRNAs have been repeatedly and stably detected in blood …