The physics of hearing: fluid mechanics and the active process of the inner ear

T Reichenbach, AJ Hudspeth - Reports on Progress in Physics, 2014 - iopscience.iop.org
Most sounds of interest consist of complex, time-dependent admixtures of tones of diverse
frequencies and variable amplitudes. To detect and process these signals, the ear employs …

Von Békésy and cochlear mechanics

ES Olson, H Duifhuis, CR Steele - Hearing research, 2012 - Elsevier
Georg Békésy laid the foundation for cochlear mechanics, foremost by demonstrating the
traveling wave that is the substrate for mammalian cochlear mechanical processing. He …

Detection of cochlear amplification and its activation

W Dong, ES Olson - Biophysical journal, 2013 - cell.com
The operation of the mammalian cochlea relies on a mechanical traveling wave that is
actively boosted by electromechanical forces in sensory outer hair cells (OHCs). This active …

Near physiological spectral selectivity of cochlear optogenetics

A Dieter, CJ Duque-Afonso, V Rankovic… - Nature …, 2019 - nature.com
Cochlear implants (CIs) electrically stimulate spiral ganglion neurons (SGNs) and partially
restore hearing to half a million CI users. However, wide current spread from intracochlear …

The frequency limit of outer hair cell motility measured in vivo

A Vavakou, NP Cooper, M van der Heijden - Elife, 2019 - elifesciences.org
Outer hair cells (OHCs) in the mammalian ear exhibit electromotility, electrically driven
somatic length changes that are thought to mechanically amplify sound-evoked vibrations …

μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve

A Dieter, E Klein, D Keppeler, L Jablonski… - EMBO molecular …, 2020 - embopress.org
Electrical cochlear implants (eCIs) partially restore hearing and enable speech
comprehension to more than half a million users, thereby re‐connecting deaf patients to the …

Cochlear outer-hair-cell power generation and viscous fluid loss

Y Wang, CR Steele, S Puria - Scientific reports, 2016 - nature.com
Since the discovery of otoacoustic emissions and outer hair cell (OHC) motility, the
fundamental question of whether the cochlea produces mechanical power remains …

Sex differences in the auditory functions of rodents

N Lin, S Urata, R Cook, T Makishima - Hearing research, 2022 - Elsevier
Background In humans, it is well known that females have better hearing than males. The
mechanism of this influence of sex on auditory function in humans is not well understood …

Cochlear partition anatomy and motion in humans differ from the classic view of mammals

S Raufer, JJ Guinan Jr… - Proceedings of the …, 2019 - National Acad Sciences
Mammals detect sound through mechanosensitive cells of the cochlear organ of Corti that
rest on the basilar membrane (BM). Motions of the BM and organ of Corti have been studied …

Energy flux in the cochlea: evidence against power amplification of the traveling wave

M van der Heijden, CPC Versteegh - … of the Association for Research in …, 2015 - Springer
Traveling waves in the inner ear exhibit an amplitude peak that shifts with frequency. The
peaking is commonly believed to rely on motile processes that amplify the wave by inserting …