Drosophila glia: Few cell types and many conserved functions

K Yildirim, J Petri, R Kottmeier, C Klämbt - Glia, 2019 - Wiley Online Library
Glial cells constitute without any dispute an essential element in providing an efficiently
operating nervous system. Work in many labs over the last decades has demonstrated that …

Neuron–glia interaction in the Drosophila nervous system

J Bittern, N Pogodalla, H Ohm, L Brüser… - Developmental …, 2021 - Wiley Online Library
Animals are able to move and react in manifold ways to external stimuli. Thus,
environmental stimuli need to be detected, information must be processed, and, finally, an …

[图书][B] Insect physiology and biochemistry

JL Nation Sr - 2022 - taylorfrancis.com
Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster

Y Yoshinari, H Kosakamoto, T Kamiyama… - Nature …, 2021 - nature.com
The enteroendocrine cell (EEC)-derived incretins play a pivotal role in regulating the
secretion of glucagon and insulins in mammals. Although glucagon-like and insulin-like …

Sex differences in intestinal carbohydrate metabolism promote food intake and sperm maturation

B Hudry, E de Goeij, A Mineo, P Gaspar… - Cell, 2019 - cell.com
Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms
remain incompletely understood. Here, we use the intestine of Drosophila melanogaster to …

Glial glucose fuels the neuronal pentose phosphate pathway for long-term memory

E de Tredern, Y Rabah, L Pasquer, J Minatchy… - Cell reports, 2021 - cell.com
Brain function relies almost solely on glucose as an energy substrate. The main model of
brain metabolism proposes that glucose is taken up and converted into lactate by astrocytes …

Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS

E Manzo, I Lorenzini, D Barrameda, AG O'Conner… - Elife, 2019 - elifesciences.org
Amyotrophic Lateral Sclerosis (ALS), is a fatal neurodegenerative disorder, with TDP-43
inclusions as a major pathological hallmark. Using a Drosophila model of TDP-43 …

Wrapping glia regulates neuronal signaling speed and precision in the peripheral nervous system of Drosophila

R Kottmeier, J Bittern, A Schoofs, F Scheiwe… - Nature …, 2020 - nature.com
The functionality of the nervous system requires transmission of information along axons
with high speed and precision. Conductance velocity depends on axonal diameter whereas …

The astrocyte: metabolic hub of the brain

LF Barros, S Schirmeier… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Astrocytic metabolism has taken center stage. Interposed between the neuron and the
vasculature, astrocytes exert control over the fluxes of energy and building blocks required …

[HTML][HTML] Enlightening brain energy metabolism

LF Barros, I Ruminot, PY Sandoval… - Neurobiology of Disease, 2023 - Elsevier
Brain tissue metabolism is distributed across several cell types and subcellular
compartments, which activate at different times and with different temporal patterns. The …