Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-
NC) and Alzheimer's disease neuropathologic change (ADNC) are each associated with …

Some individuals are able to maintain their cognitive abilities despite the presence of
significant Alzheimer's Disease (AD) neuropathological changes. This discrepancy between …

Alzheimer disease (AD) is a significant cause of morbidity and mortality worldwide, with
limited treatment options and considerable diagnostic challenges. Identification and …

The medial temporal lobe (MTL) is a hotspot for neuropathology, and measurements of MTL
atrophy are often used as a biomarker for cognitive decline associated with …

Background: The strongest risk factor for the development of Alzheimer's disease (AD) is
age. The progression of Braak stage and Thal phase with age has been demonstrated …

Pure limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes
(pure LATE-NC) is a term used to describe brains with LATE-NC but lacking intermediate or …

Some individuals show a discrepancy between cognition and the amount of
neuropathological changes characteristic for Alzheimer's disease (AD). This phenomenon …

Aging refers to progressive physiological changes in a cell, an organ, or the whole body of
an individual, over time. Aging-related diseases are highly prevalent and could impact an …

O cular involvement is a common and well-known presenting or defining manifestation of
many important systemic and neuro-ophthalmic diseases, including multiple vascular …

Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-
NC) and Alzheimer's disease neuropathologic change (ADNC) are each associated with …