Background Nicotine replacement therapy (NRT) aims to replace nicotine from cigarettes to
ease the transition from cigarette smoking to abstinence. It works by reducing the intensity of …

Withdrawal is an essential component of classical addiction theory; it is a vital manifestation
of dependence and motivates relapse. However, the traditional conceptualization of …

Background Substance use and depression often co-occur, complicating treatment of both
substance use and depression. Despite research documenting age-related trends in both …

Purpose To examine time-varying associations between predictors of recent multiple sexual
partners from middle adolescence through young adulthood. Methods We examined …

Introduction Early onset of substance use is a risk factor for later drug use, abuse, and
dependence. This study examines how the rate of nicotine dependence differs as a function …

Purpose The purpose of this study was to describe historical trends in rates of recent
substance use and associations between marijuana and other substances, among US high …

We are incredibly grateful for the support of our many colleagues. We would first like to thank
Drs. Runze Li and John Dziak for their key intellectual contributions to time-varying effect …

Time-varying effect modeling (TVEM), a statistical approach that enables researchers to
estimate dynamic associations between variables across time, holds enormous potential to …

Time‐varying effect modeling (TVEM), a statistical technique for modeling dynamic patterns
of change, presents new opportunities to study biobehavioral health processes. TVEM is …

Background Electronic cigarettes (e-cigarettes) are increasingly used by US adolescents
and may be a gateway to traditional cigarette use. We examine rates of both products by age …