Over the years, transition metal catalyzed reactions, such as C–H activation reaction, have
brought in a paradigm shift in the practice of organic synthesis. Many complex targets could …

Aromatic amines are widely recognized as some of the most important scaffolds in various
functional molecules, such as pharmaceuticals and materials. Two reactions have been …

A palladium‐catalyzed chemoselective coupling of readily available bicyclo [1.1. 1] pentanyl
alcohols (BCP− OH) with various halides is reported, which offers expedient approaches to …

Density functional theory was employed in order to elucidate the mechanism and factors that
lead to the observed regioselectivity in the dialkylbiarylphosphine (Phos)/Pd-catalyzed C–C …

The functionalization of simple arenes without coordinating directing groups is a challenge.
Besides facing the task of cleaving the sluggish C–H bond, the process is hampered by the …

The search for more effective and highly selective C–H bond oxidation of accessible
hydrocarbons and biomolecules is a greatly attractive research mission. The elucidating of …

The Catellani-type palladium/norbornene-cocatalyzed ortho-amination of aryl halides has
been widely applied. Although a Pd (0)/Pd (II)/Pd (IV) mechanism is generally adopted …

Transition-metal-catalyzed enantioselective C–O bond constructions via
hydrofunctionalization involving the use of O-based nucleophiles are an important topic in …

Density functional theory (DFT) calculations have been conducted to gain insight into the
unique formation of the branched alkylation product in the PdII-catalyzed defluorinative …

Transition metal-catalyzed spiroannulations are practical strategies for constructing
spirocyclic skeletons of pharmaceutical and biological significance, yet the microscopic …