Updated clinical perspectives and challenges of chimeric antigen receptor-T cell therapy in colorectal cancer and invasive breast cancer

Y Cao, SK Efetov, M He, Y Fu, NM Beeraka… - Archivum Immunologiae …, 2023 - Springer
In recent years, the incidence of colorectal cancer (CRC) and breast cancer (BC) has
increased worldwide and caused a higher mortality rate due to the lack of selective anti …

Classical angiogenic signaling pathways and novel anti-angiogenic strategies for colorectal cancer

M Cao, Y Wang, G Lu, H Qi, P Li, X Dai… - Current Issues in Molecular …, 2022 - mdpi.com
Although productive progress has been made in colorectal cancer (CRC) researchs, CRC is
the second most frequent type of malignancy and the major cause of cancer-related death …

A systematic review and meta-analysis of trifluridine/tipiracil plus bevacizumab for the treatment of metastatic colorectal cancer: evidence from real-world series

IA Voutsadakis - Current Oncology, 2023 - mdpi.com
Background: Colorectal cancer is the most prevalent gastrointestinal neoplasm. When
metastatic, the disease has limited systemic treatment options. Novel targeted therapies …

Innovations in colorectal cancer treatment: trifluridine and tipiracil with bevacizumab for improved outcomes–a review

T Rais, R Riaz, T Siddiqui, A Shakeel… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Colorectal cancer ranks second in cancer-related deaths throughout the world. At the time of
diagnosis, at least 20% of the patients with CRC had already developed metastases …

Combining moderate dosage of Bevacizumab with TAS-102 provides longer progression-free time in refractory metastatic colorectal Cancer

KY Tseng, MY Yang, WS Chen, JK Jiang… - International Journal of …, 2024 - Springer
Purpose We aimed to evaluate the efficacy of moderate doses of bevacizumab in
combination with TAS-102 for the treatment of refractory metastatic colorectal cancer …

[HTML][HTML] Bevacizumab mitigates codon-specific effects of trifluridine/tipiracil on efficacy outcome parameters in metastatic colorectal cancer

B Doleschal, H Taghizadeh, T Lentner, JM Riedl… - ESMO open, 2023 - Elsevier
Background Molecular informed therapy changed treatment patterns of metastatic colorectal
cancer (mCRC). Recently KRAS G12, the most prevalent RAS mutation in mCRC, was …

RETRO-TAS, a Retrospective Observational Study of Trifluridine/Tipiracil in Chemorefractory Metastatic Colorectal Cancer

A Koumarianou, A Ntavatzikos, D Symeonidis… - Biomedicines, 2023 - mdpi.com
Background: Trifluridine/tipiracil (FTD/TPI) is an oral antimetabolite agent comprised of
trifluridine, a thymidine-based nucleoside analogue that inhibits cell proliferation following …

Combination of Modest Dosage of Bevacizumab with TAS-102 Provided the Comparable Efficacy in Treating Refractory Metastatic Colorectal Cancer

KY Tseng, MY Yang, WS Chen, JK Jiang, HS Wang… - 2024 - researchsquare.com
Background Given that the combination of bevacizumab and TAS-102 is used to treat
refractory metastatic colorectal cancer (mCRC), we aimed to evaluate the efficacy of modest …