Repair of spinal cord injury with neuronal relays: from fetal grafts to neural stem cells

JF Bonner, O Steward - Brain research, 2015 - Elsevier
Spinal cord injury (SCI) disrupts the long axonal tracts of the spinal cord leading to
devastating loss of function. Cell transplantation in the injured spinal cord has the potential …

A systematic review of exercise training to promote locomotor recovery in animal models of spinal cord injury

CR Battistuzzo, RJ Callister, R Callister… - Journal of …, 2012 - liebertpub.com
In the early 1980s experiments on spinalized cats showed that exercise training on the
treadmill could enhance locomotor recovery after spinal cord injury (SCI). In this review, we …

GDNF rescues the fate of neural progenitor grafts by attenuating Notch signals in the injured spinal cord in rodents

M Khazaei, CS Ahuja, H Nakashima… - Science translational …, 2020 - science.org
Neural progenitor cell (NPC) transplantation is a promising strategy for the treatment of
spinal cord injury (SCI). In this study, we show that injury-induced Notch activation in the …

Combination treatment with anti‐Nogo‐A and chondroitinase ABC is more effective than single treatments at enhancing functional recovery after spinal cord injury

RR Zhao, MR Andrews, D Wang… - European Journal of …, 2013 - Wiley Online Library
Anti‐Nogo‐A antibody and chondroitinase ABC (Ch ABC) enzyme are two promising
treatments that promote functional recovery after spinal cord injury (SCI). Treatment with …

The need for speed in rodent locomotion analyses

RJ Batka, TJ Brown, KP Mcmillan… - The Anatomical …, 2014 - Wiley Online Library
Locomotion analysis is now widely used across many animal species to understand the
motor defects in disease, functional recovery following neural injury, and the effectiveness of …

Rehabilitative training in animal models of spinal cord injury

A Torres-Espín, E Beaudry, K Fenrich… - Journal of …, 2018 - liebertpub.com
Rehabilitative motor training is currently one of the most widely used approaches to promote
moderate recovery following injuries of the central nervous system. Such training is …

Myelin repair of spinal cord injury in adult mice induced by treadmill training upregulated peroxisome proliferator‐activated receptor gamma coactivator 1 alpha

H Su, H Luo, Y Wang, Q Zhao, Q Zhang, Y Zhu, L Pan… - Glia, 2024 - Wiley Online Library
Growing evidence has proven the efficacy of physical exercise in remyelination and motor
function performance after spinal cord injury (SCI). However, the molecular mechanisms of …

[HTML][HTML] Quantitative gait analysis of long-term locomotion deficits in classical unilateral striatal intracerebral hemorrhage rat model

Y Liu, LJ Ao, G Lu, E Leong, Q Liu, XH Wang… - Behavioural brain …, 2013 - Elsevier
Gait analysis is a systematic collection of quantitative information on bodily movements
during locomotion. Gait analysis has been employed clinically in stroke patients for their …

Dual motor cortex and spinal cord neuromodulation improves rehabilitation efficacy and restores skilled locomotor function in a rat cervical contusion injury model

H Sharif, H Alexander, A Azam, JH Martin - Experimental neurology, 2021 - Elsevier
Motor recovery after spinal cord injury is limited due to sparse descending pathway axons
caudal to the injury. Rehabilitation is the primary treatment for paralysis in humans with SCI …

Electroacupuncture improves neurobehavioral function and brain injury in rat model of intracerebral hemorrhage

Y Zhu, L Deng, H Tang, X Gao, Y Wang, K Guo… - Brain Research …, 2017 - Elsevier
Acupuncture has been widely used as a treatment for stroke in China for a long time.
Recently, studies have demonstrated that electroacupuncture (EA) can accelerate …