[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer
X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
Going circular: history, present, and future of circRNAs in cancer
To date, thousands of highly abundant and conserved single-stranded RNA molecules
shaped into ring structures (circRNAs) have been identified. CircRNAs are multifunctional …
shaped into ring structures (circRNAs) have been identified. CircRNAs are multifunctional …
The bioinformatics toolbox for circRNA discovery and analysis
Circular RNAs (circRNAs) are a unique class of RNA molecule identified more than 40 years
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer
X Yang, T Ye, H Liu, P Lv, C Duan, X Wu, K Jiang, H Lu… - Molecular cancer, 2021 - Springer
Circular RNAs (circRNAs), which are single-stranded closed-loop RNA molecules lacking
terminal 5′ caps and 3′ poly (A) tails, are attracting increasing scientific attention for their …
terminal 5′ caps and 3′ poly (A) tails, are attracting increasing scientific attention for their …
Role of circular RNAs in brain development and CNS diseases
In mammals, many classes of noncoding RNAs (ncRNAs) are expressed at a much higher
level in the brain than in other organs. Recent studies have identified a new class of ncRNAs …
level in the brain than in other organs. Recent studies have identified a new class of ncRNAs …
Nanopore sequencing of brain-derived full-length circRNAs reveals circRNA-specific exon usage, intron retention and microexons
Circular RNA (circRNA) is a class of covalently joined non-coding RNAs with functional roles
in a wide variety of cellular processes. Their composition shows extensive overlap with …
in a wide variety of cellular processes. Their composition shows extensive overlap with …
CircRNAs in colorectal cancer: potential biomarkers and therapeutic targets
Y Zhang, J Luo, W Yang, WC Ye - Cell death & disease, 2023 - nature.com
Globally, colorectal cancer (CRC) is the third most prevalent cancer and the second leading
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …
Circular RNA circLMO1 Suppresses Cervical Cancer Growth and Metastasis by Triggering miR-4291/ACSL4-Mediated Ferroptosis
R Ou, S Lu, L Wang, Y Wang, M Lv, T Li, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Background A number of studies have demonstrated that circular RNA (circRNA) plays a
critical role in tumorigenesis and tumor progression. However, the biological effects of most …
critical role in tumorigenesis and tumor progression. However, the biological effects of most …
[HTML][HTML] Circular RNA hsa_circ_0000515 acts as a miR-326 sponge to promote cervical cancer progression through up-regulation of ELK1
Q Tang, Z Chen, L Zhao - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
This study investigates the role of circular RNA (circRNA) hsa_circ_0000515 in cervical
cancer and the underlying mechanism associated with microRNA-326 (miR-326) …
cancer and the underlying mechanism associated with microRNA-326 (miR-326) …
Emerging function and potential diagnostic value of circular RNAs in cancer
X Cui, J Wang, Z Guo, M Li, M Li, S Liu, H Liu, W Li… - Molecular cancer, 2018 - Springer
As a novel class of endogenous RNAs, circRNAs, have a covalently closed continuous loop,
with neither a 5'to 3'polarity, nor a polyadenylated tail. Numerous circRNAs have been …
with neither a 5'to 3'polarity, nor a polyadenylated tail. Numerous circRNAs have been …