The concept that preeclampsia is a multisystemic syndrome is appreciated in both research and clinical care. Our understanding of pathophysiology recognizes the role of inflammation …
R Fox, J Kitt, P Leeson, CYL Aye… - Journal of clinical …, 2019 - mdpi.com
Hypertensive disorders of pregnancy affect up to 10% of pregnancies worldwide, which includes the 3%–5% of all pregnancies complicated by preeclampsia. Preeclampsia is …
The pharmacokinetics of vitamin C (vitC) is indeed complex. Regulated primarily by a family of saturable sodium dependent vitC transporters (SVCTs), the absorption and elimination …
Vitamin C (Ascorbic Acid), the antiscorbutic vitamin, cannot be synthesized by humans and other primates, and has to be obtained from diet. Ascorbic acid is an electron donor and acts …
DI Chiarello, C Abad, D Rojas, F Toledo… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The role of oxidative stress in the physiopathology of human pregnancy is of particular interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …
Background Existing evidence on the effects of race and ethnicity on pregnancy outcomes is restricted to individual studies done within specific countries and health systems. We aimed …
Preeclampsia is diagnosed in women presenting with new onset hypertension accompanied by proteinuria or other signs of severe organ dysfunction in the second half of pregnancy …
The mechanistic properties of two dietary antioxidants that are required by humans, vitamins C and E, are discussed relative to their biological effects. Vitamin C (ascorbic acid) is an …
B Sibai, G Dekker, M Kupferminc - The Lancet, 2005 - thelancet.com
Pre-eclampsia is a major cause of maternal mortality (15–20% in developed countries) and morbidities (acute and long-term), perinatal deaths, preterm birth, and intrauterine growth …