➤ There are a number of potential clinical applications for growth factors in the enhancement
of bone repair, including acceleration of fracture-healing, treatment of established …

Over the past several decades, recombinant human bone morphogenetic proteins (rhBMPs)
have been the most extensively studied and widely used osteoinductive agents for clinical …

The development of bone tissue engineering is directly related to changes in materials
technology. While the inclusion of materials requirements is standard in the design process …

Background: Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and
clinical trials are currently underway to evaluate the ability of certain BMPs to promote …

Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily and have
diverse functions during development and organogenesis. BMPs play a major role in …

Efficacious bone regeneration could revolutionize the clinical management of bone and
musculoskeletal disorders. Although several bone morphogenetic proteins (BMPs)(mostly …

The role of bone morphogenetic proteins (BMPs) in bone healing has been shown in
numerous animal models. To date, at least 20 BMPs have been identified, some of which …

Over the past 30 years, an enormous array of biomaterials proposed as ideal scaffolds for
cell growth have emerged, yet few have demonstrated clinical efficacy. Biomaterials …

Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily and play a
critical role in skeletal development, bone formation and stem cell differentiation. Disruptions …

Healing of fractures is dependent on vascularization of bone, which is in turn promoted by
VEGF. It was shown that 0.1 and 1 mg of pVEGF165‐GAM led to a significant increase in …