Bioorthogonal catalysis for treatment of solid tumors using thermostable, self-assembling, single enzyme nanoparticles and natural product conversion with indole-3 …

S Sadeghi, ND Masurkar, G Vallerinteavide Mavelli… - ACS …, 2022 - ACS Publications
Bioorthogonal catalysis (BC) generates chemical reactions not present in normal physiology
for the purpose of disease treatment. Because BC catalytically produces the desired therapy …

T Cell Activating Thermostable Self‐Assembly Nanoscaffold Tailored for Cellular Immunity Antigen Delivery

J Zhang, J Yang, Q Li, R Peng, S Fan, H Yi… - Advanced …, 2023 - Wiley Online Library
Antigen delivery based on non‐virus‐like particle self‐associating protein nanoscffolds,
such as Aquifex aeolicus lumazine synthase (AaLS), is limited due to the immunotoxicity …

Gastrointestinal tract stabilized protein delivery using disulfide thermostable exoshell system

S Sadeghi, G Vallerinteavide Mavelli… - International Journal of …, 2022 - mdpi.com
Thermostable exoshells (tES) are engineered proteinaceous nanoparticles used for the
rapid encapsulation of therapeutic proteins/enzymes, whereby the nanoplatform protects the …

New Trends in Freeze-Drying of Pharmaceutical Products

R Pisano, D Fissore - Pharmaceutics, 2023 - mdpi.com
Freeze-drying, also known as lyophilization, is a process that facilitates the removal of water
through sublimation from a frozen product (primary drying). Subsequently, the (low) target …

Laboratory Scale Production of Complex Proteins Using Charge Complimentary Nanoenvironments

G Vallerinteavide Mavelli, S Sadeghi… - Protein Cages: Design …, 2023 - Springer
Protein refolding is a crucial procedure in bacterial recombinant expression. Aggregation
and misfolding are the two challenges that can affect the overall yield and specific activity of …

Check Chapter 19 updates

Y Nakahara, Y Endo, I Inoue - Protein Cages: Design, Structure …, 2023 - books.google.com
Ferritin is one of the most promising drug delivery system (DDS) carriers because of its
uniform nanosize, biodistribution, efficient cellular uptake, and biocompatibility …

Translational Applications of Thermostable Exoshells: A Detailed Study

S Sadeghi - 2022 - search.proquest.com
Nanomedicine refers to the use of diverse nanostructured materials having clinical
applications, ranging from contrast agents in imaging to vehicles for targeted delivery of …