A forward vision for chemodynamic therapy: issues and opportunities

P Zhao, H Li, W Bu - Angewandte Chemie International Edition, 2023 - Wiley Online Library
Since the insight to fuse Fenton chemistry and nanomedicine into cancer therapy, great
signs of progress have been made in the field of chemodynamic therapy (CDT). However …

Bioengineered nanogels for cancer immunotherapy

X Ma, SJ Li, Y Liu, T Zhang, P Xue, Y Kang… - Chemical Society …, 2022 - pubs.rsc.org
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Stimuli-responsive polymer-based nanosystems for cancer theranostics

D Wei, Y Sun, H Zhu, Q Fu - ACS nano, 2023 - ACS Publications
Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …

An Activatable Phototheranostic Probe for Anti‐hypoxic Type I Photodynamic‐and Immuno‐Therapy of Cancer

M Zhao, Y Zhang, J Miao, H Zhou, Y Jiang… - Advanced …, 2024 - Wiley Online Library
Photodynamic therapy (PDT), which utilizes type I photoreactions, has great potential as an
effective cancer treatment because of its hypoxia‐tolerant superiority over the commonly …

Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy

M Sun, Z Liu, L Wu, J Yang, J Ren… - Journal of the American …, 2023 - ACS Publications
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …

Checkpoint nano‐PROTACs for activatable cancer photo‐immunotherapy

C Zhang, M Xu, S He, J Huang, C Xu… - Advanced Materials, 2023 - Wiley Online Library
Checkpoint immunotherapy holds great potential to treat malignancies via blocking the
immunosuppressive signaling pathways, which however suffers from inefficiency and off …

Leveraging semiconducting polymer nanoparticles for combination cancer immunotherapy

J Wu, K Pu - Advanced Materials, 2024 - Wiley Online Library
Cancer immunotherapy has become a promising method for cancer treatment, bringing
hope to advanced cancer patients. However, immune‐related adverse events caused by …

Free radical as a double-edged sword in disease: Deriving strategic opportunities for nanotherapeutics

L Zhu, M Luo, Y Zhang, F Fang, M Li, F An… - Coordination chemistry …, 2023 - Elsevier
Free radicals, usually containing one or more unpaired electrons, are extremely unstable
and highly reactive with other biological molecules. Recently, there has been increasing …

A Semiconducting Iron‐Chelating Nano‐immunomodulator for Specific and Sensitized Sono‐metallo‐immunotherapy of Cancer

S He, J Yu, M Xu, C Zhang, C Xu… - Angewandte …, 2023 - Wiley Online Library
Sono‐immunotherapy holds great potential for deep tumor inhibition; however, smart sono‐
therapeutic agents to simultaneously eliminate 'domestic'tumor cells and regulate the …

Highly efficient photosensitizers with molecular vibrational torsion for cancer photodynamic therapy

X Zhou, C Shi, S Long, Q Yao, H Ma, K Chen… - ACS Central …, 2023 - ACS Publications
The development of highly effective photosensitizers (PSs) for photodynamic therapy
remains a great challenge at present. Most PSs rely on the heavy-atom effect or the spin …