Chemotherapeutic agents have certain limitations when it comes to treating cancer, the most
important being severe side effects along with multidrug resistance developed against them …

In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …

Highlights•Dendrimers are efficient nanocarriers having biomedical and diagnostic
application potentials.•Dendrimers can be efficiently encapsulated with drugs by host–guest …

Dendrimers are new class of polymeric materials. It is generally described as a
macromolecule, which is characterized by its extensively branched 3D structure that …

The drug candidates coming from combinatorial chemistry research and/or the drugs
selected from biologically based high-throughput screening are quite often very lipophilic, as …

RNA interference therapeutics afford the potential to silence target gene expression
specifically, thereby blocking production of disease-causing proteins. The development of …

The potential use of antisense and siRNA oligonucleotides as therapeutic agents has
elicited a great deal of interest. However, a major issue for oligonucleotide-based …

Ligand-mediated targeting of drugs especially in anticancer drug delivery is an effective
approach. Dendrimers, due to unique surface topologies, can be a choice in this context. In …

1. INTRODUCTION The host− guest chemistry was first developed with the discovery of
crown ethers by Pederson in the 1960s. 1, 2 It was found that the cyclic crown ethers are …

The performance of biosensors, ie the sensitivity, specificity, linearity, reusability, chemical
stability, and reproducibility is critically dependent on the biofunctionalization of the sensor …