Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain
S Alfonso-Loeches, C Guerri - Critical reviews in clinical laboratory …, 2011 - Taylor & Francis
The brain is one of the major target organs of alcohol actions. Alcohol abuse can lead to
alterations in brain structure and functions and, in some cases, to neurodegeneration …
alterations in brain structure and functions and, in some cases, to neurodegeneration …
[HTML][HTML] Mechanisms of alcohol-induced damage to the developing nervous system
CR Goodlett, KH Horn - Alcohol Research & Health, 2001 - ncbi.nlm.nih.gov
Numerous mechanisms likely contribute to the damaging effects of prenatal alcohol
exposure on the developing fetus and particularly the developing central nervous system …
exposure on the developing fetus and particularly the developing central nervous system …
Acute and chronic effects of ethanol on learning-related synaptic plasticity
CF Zorumski, S Mennerick, Y Izumi - Alcohol, 2014 - Elsevier
Alcoholism is associated with acute and long-term cognitive dysfunction including memory
impairment, resulting in substantial disability and cost to society. Thus, understanding how …
impairment, resulting in substantial disability and cost to society. Thus, understanding how …
A theory explaining biological correlates of criminality
E Lee - Recent Developments in Criminological Theory, 2017 - taylorfrancis.com
Despite major advances in understanding the biological basis of human behaviour, the most
popular theories of criminal behaviour remain restricted to those that consider only learning …
popular theories of criminal behaviour remain restricted to those that consider only learning …
A limited access mouse model of prenatal alcohol exposure that produces long‐lasting deficits in hippocampal‐dependent learning and memory
ML Brady, AM Allan, KK Caldwell - Alcoholism: Clinical and …, 2012 - Wiley Online Library
Background: It has been estimated that approximately 12% of women consume alcohol at
some time during their pregnancy, and as many as 5% of children born in the United States …
some time during their pregnancy, and as many as 5% of children born in the United States …
The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) …
JP Schroeder, DH Overstreet, CW Hodge - Psychopharmacology, 2005 - Springer
Rationale Recent research indicates that blockade of mGluR5 modifies the reinforcing
properties of ethanol. Objectives The present studies examined the effects of mGluR5 …
properties of ethanol. Objectives The present studies examined the effects of mGluR5 …
Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus
ML Brady, MR Diaz, A Iuso, JC Everett… - Journal of …, 2013 - Soc Neuroscience
Although it is well documented that heavy consumption of alcohol during pregnancy impairs
brain development, it remains controversial whether moderate consumption causes …
brain development, it remains controversial whether moderate consumption causes …
Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high …
BACKGROUND: Systemic modulation of Group I and II metabotropic glutamate receptors
(mGluRs) regulate ethanol self-administration in a variety of animal models. Although these …
(mGluRs) regulate ethanol self-administration in a variety of animal models. Although these …
The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice
Rationale Many of the biochemical, physiological, and behavioral effects of ethanol are
known to be mediated by ionotropic glutamate receptors. Emerging evidence implicates …
known to be mediated by ionotropic glutamate receptors. Emerging evidence implicates …
[HTML][HTML] Focus on: neurotransmitter systems
Neurotransmitter systems have been long recognized as important targets of the
developmental actions of alcohol (ie, ethanol). Short-and long-term effects of ethanol on …
developmental actions of alcohol (ie, ethanol). Short-and long-term effects of ethanol on …