Lipids represent the most abundant molecular type in the brain, with a fat content of∼ 60%
of the dry brain weight in humans. Despite this fact, little attention has been paid to …

Background Defective mitochondria and aberrant brain mitochondrial bioenergetics are
consistent features in syndromic intellectual disability disorders, such as Rett syndrome …

Emotions and behavior can be affected by social chemosignals from conspecifics. For
instance, olfactory signals from stressed individuals induce stress-like physiological and …

As central nervous system (CNS)-related disorders present an increasing cause of global
morbidity, mortality, and high pressure on our healthcare system, there is an urgent need for …

Background The prevalence of vascular cognitive impairment induced by chronic cerebral
ischemia (CCI) is increasing year by year. Cognitive-exercise dual-task intervention has …

PM2. 5 exposure is a challenging environmental issue that is closely related to cognitive
development impairment; however, currently, relevant means for prevention and treatment …

Chlorogenic acid (CGA) is a dietary phenolic acid widely distributed in daily food and plants,
but its role in vascular dementia (VaD) is still unclear. Hence, this study aimed to investigate …

The endocannabinoid system is an essential intercellular signaling mechanism with a
decisive role in many physiological functions of the brain. Endocannabinoids (eCBs) …

Background: Circadian rhythms exist across species, and circadian rhythm disorder (CRD)
occurs in people of all ages and is prevalent in those with age-related neurodegenerative …

The endocannabinoid system (ECS) is a complex neuromodulatory network that has
attracted tremendous research interest over the past 50 years. The vast majority of our …