Growing evidence suggests that aberrant epigenetic regulation of gene function is strongly
related to the genesis of cancer. Unlike genetic mutations, the ability to reprogram the …

Atherosclerosis, the main contributor to coronary heart disease, is characterised by an
accumulation of lipids such as cholesterol in the arterial wall. Reverse cholesterol transport …

The field of non-coding RNA (ncRNA) has made significant progress in understanding the
pathogenesis of diseases and has broadened our knowledge towards their targeting …

MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …

Silibinin is a natural plant polyphenol with high antioxidant and anticancer properties, which
causes broad-spectrum efficacy against cancer, including cell cycle arrest and apoptosis in …

Breast cancer is one of the most common neoplasms worldwide, and in spite of clinical and
pharmacological advances, it is still a clinical problem, causing morbidity and mortality. On …

Despite tremendous achievements in the field of targeted cancer therapy, chemotherapy is
still the main treatment option, which is challenged by acquired drug resistance. Various …

Recently, technologies in designing novel drug delivery strategies have evolved to
overcome challenges like biological barriers. Nanobiomaterials have shown significant …

Background: Tumor cells may be expressed as a result of oxidative stress. The extent of
oxidative stress correlates with the aggressive and metastatic potency of cancer. Objective …

This study demonstrated a chemotherapy drug-free delivery system for breast cancer
treatment based on a simple DNA nanostructure composed of sequence 1 containing ATP …