The spread and evolution of rabies virus: conquering new frontiers

CR Fisher, DG Streicker, MJ Schnell - Nature Reviews Microbiology, 2018 - nature.com
Rabies is a lethal zoonotic disease that is caused by lyssaviruses, most often rabies virus.
Despite control efforts, sporadic outbreaks in wildlife populations are largely unpredictable …

[HTML][HTML] Lyssaviruses and rabies: current conundrums, concerns, contradictions and controversies

C Rupprecht, I Kuzmin, F Meslin - F1000Research, 2017 - ncbi.nlm.nih.gov
Lyssaviruses are bullet-shaped, single-stranded, negative-sense RNA viruses and the
causative agents of the ancient zoonosis rabies. Africa is the likely home to the ancestors of …

Large-scale phylogenomic analysis reveals the complex evolutionary history of rabies virus in multiple carnivore hosts

C Troupin, L Dacheux, M Tanguy, C Sabeta… - PLoS …, 2016 - journals.plos.org
The natural evolution of rabies virus (RABV) provides a potent example of multiple host
shifts and an important opportunity to determine the mechanisms that underpin viral …

Integrating full and partial genome sequences to decipher the global spread of canine rabies virus

A Holtz, G Baele, H Bourhy, A Zhukova - Nature Communications, 2023 - nature.com
Despite the rapid growth in viral genome sequencing, statistical methods face challenges in
handling historical viral endemic diseases with large amounts of underutilized partial …

Making genomic surveillance deliver: A lineage classification and nomenclature system to inform rabies elimination

K Campbell, RJ Gifford, J Singer, V Hill… - PLoS …, 2022 - journals.plos.org
The availability of pathogen sequence data and use of genomic surveillance is rapidly
increasing. Genomic tools and classification systems need updating to reflect this. Here …

[HTML][HTML] Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes

K Brunker, G Jaswant, SM Thumbi… - Wellcome Open …, 2020 - ncbi.nlm.nih.gov
Genomic surveillance is an important aspect of contemporary disease management but has
yet to be used routinely to monitor endemic disease transmission and control in low-and …

Landscape attributes governing local transmission of an endemic zoonosis: Rabies virus in domestic dogs

K Brunker, P Lemey, DA Marston, AR Fooks… - Molecular …, 2018 - Wiley Online Library
Landscape heterogeneity plays an important role in disease spread and persistence, but
quantifying landscape influences and their scale dependence is challenging. Studies have …

Portable rabies virus sequencing in canine rabies endemic countries using the Oxford Nanopore MinION

CM Gigante, G Yale, RE Condori, NC Costa, NV Long… - Viruses, 2020 - mdpi.com
As countries with endemic canine rabies progress towards elimination by 2030, it will
become necessary to employ techniques to help plan, monitor, and confirm canine rabies …

Rabies elimination research: juxtaposing optimism, pragmatism and realism

S Cleaveland, K Hampson - Proceedings of the Royal …, 2017 - royalsocietypublishing.org
More than 100 years of research has now been conducted into the prevention, control and
elimination of rabies with safe and highly efficacious vaccines developed for use in human …

Mathematical modelling and phylodynamics for the study of dog rabies dynamics and control: A scoping review

M Layan, S Dellicour, G Baele… - PLOS Neglected …, 2021 - journals.plos.org
Background Rabies is a fatal yet vaccine-preventable disease. In the last two decades,
domestic dog populations have been shown to constitute the predominant reservoir of …