The compatibility of biomaterials is critical to their structural and biological function in
medical applications. The immune system is the first responder to tissue trauma and to a …

Mesenchymal stem cells (MSCs) are multipotent cells which can proliferate and replace
dead cells in the body. MSCs also secrete immunomodulatory molecules, creating a …

Stem cells are the central element of regenerative medicine (RM). However, in many clinical
applications, the use of scaffolds fabricated with biomaterials is required. In this sense …

Cancer stands as one of the most leading causes of death worldwide, while one of the most
significant challenges in treating it is revealing novel alternatives to predict, diagnose, and …

Angiogenesis is touted as a fundamental procedure in the regeneration and restoration of
different tissues. The induction of de novo blood vessels seems to be vital to yield a …

There is no consensus on the true meaning of clinical regenerative endodontics, and there
is confusion over the concept and the term. Commonly used terms include revitalization and …

Long thought of to be vesicles that primarily recycled waste biomolecules from cells,
extracellular vesicles (EVs) have now emerged as a new class of nanotherapeutics for …

Sarcopenia is characterized by reduced skeletal muscle mass and strength in older
individuals. It is one of the leading cause of physical limitation in older adults, and …

Traumas and chronic damages can hamper the regenerative power of nervous, muscle, and
connective tissues. Tissue engineering approaches are promising therapeutic tools, aiming …

Musculoskeletal disorders such as osteoporosis and rheumatoid arthritis are responsible for
more than 25k deaths every year in the European Union and constitute a chronic burden on …