[HTML][HTML] Brown and beige adipose tissues in health and disease
L Rui - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
Brown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue
(BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat …
(BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat …
Brown adipose tissue: updates in cellular and molecular biology
TCL Bargut, MB Aguila, CA Mandarim-de-Lacerda - Tissue and Cell, 2016 - Elsevier
Brown adipose tissue (BAT) is mainly composed of adipocytes, it is highly vascularized and
innervated, and can be activated in adult humans. Brown adipocytes are responsible for …
innervated, and can be activated in adult humans. Brown adipocytes are responsible for …
Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice
V Efthymiou, L Ding, M Balaz, W Sun… - Nature …, 2023 - nature.com
The current obesity epidemic and high prevalence of metabolic diseases necessitate
efficacious and safe treatments. Brown adipose tissue in this context is a promising target …
efficacious and safe treatments. Brown adipose tissue in this context is a promising target …
Genetic diversity and population structure of six autochthonous pig breeds from Croatia, Serbia, and Slovenia
Background The importance of local breeds as genetic reservoirs of valuable genetic
variation is well established. Pig breeding in Central and South-Eastern Europe has a long …
variation is well established. Pig breeding in Central and South-Eastern Europe has a long …
Dissociation Between Brown Adipose Tissue 18F-FDG Uptake and Thermogenesis in Uncoupling Protein 1–Deficient Mice
18F-FDG PET imaging is routinely used to investigate brown adipose tissue (BAT)
thermogenesis, which requires mitochondrial uncoupling protein 1 (UCP1). It remains …
thermogenesis, which requires mitochondrial uncoupling protein 1 (UCP1). It remains …
A compendium of G-protein–coupled receptors and cyclic nucleotide regulation of adipose tissue metabolism and energy expenditure
With the ever-increasing burden of obesity and Type 2 diabetes, it is generally
acknowledged that there remains a need for developing new therapeutics. One potential …
acknowledged that there remains a need for developing new therapeutics. One potential …
Theobromine alleviates diet-induced obesity in mice via phosphodiesterase-4 inhibition
MH Jang, S Mukherjee, MJ Choi, NH Kang… - European journal of …, 2020 - Springer
Purpose Modern science has given much attention to the treatment of obesity by activating
brown adipose tissue (BAT) and browning of white adipose tissue (WAT). Recent studies …
brown adipose tissue (BAT) and browning of white adipose tissue (WAT). Recent studies …
[HTML][HTML] Uncoupling mechanism and redox regulation of mitochondrial uncoupling protein 1 (UCP1)
P Ježek, M Jabůrek, RK Porter - Biochimica et Biophysica Acta (BBA) …, 2019 - Elsevier
Brown adipose tissue (BAT) and brown in white (brite) adipose tissue, termed also beige
adipose tissue, are major sites of mammalian nonshivering thermogenesis. Mitochondrial …
adipose tissue, are major sites of mammalian nonshivering thermogenesis. Mitochondrial …
Cyclic nucleotide phosphodiesterases: New targets in the metabolic syndrome?
C Lugnier, A Meyer, S Talha, B Geny - Pharmacology & therapeutics, 2020 - Elsevier
Metabolic diseases have a tremendous impact on human morbidity and mortality. Numerous
targets regulating adenosine monophosphate kinase (AMPK) have been identified for …
targets regulating adenosine monophosphate kinase (AMPK) have been identified for …
Role of cAMP and cGMP signaling in brown fat
L Reverte-Salisa, A Sanyal, A Pfeifer - Brown Adipose Tissue, 2019 - Springer
Cold-induced activation of brown adipose tissue (BAT) is mediated by norepinephrine and
adenosine that are released during sympathetic nerve activation. Both signaling molecules …
adenosine that are released during sympathetic nerve activation. Both signaling molecules …