The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

Many cellular processes rely on precise and timely deformation of the cell membrane. While
many proteins participate in membrane reshaping and scission, usually in highly specialized …

Abstract FAM134B/RETREG1 is a selective ER-phagy receptor that regulates the size and
shape of the endoplasmic reticulum. The structure of its reticulon-homology domain (RHD) …

B lymphocytes recognize bacterial or viral antigens via different classes of the B cell antigen
receptor (BCR). Protrusive structures termed microvilli cover lymphocyte surfaces, and are …

Cellular membranes self-assemble from and interact with various molecular species. Each
molecule locally shapes the lipid bilayer, the soft elastic core of cellular membranes. The …

α-Synuclein is a small neuronal protein enriched at presynaptic termini. It is hypothesized to
play a role in neurotransmitter release and synaptic vesicle cycling, while the formation of α …

Membrane-active cytoskeletal elements, such as FtsZ, septin or actin, form filamentous
polymers able to induce and stabilize curvature on cellular membranes. In order to emulate …

The influenza A M2 homotetrameric channel consists of four transmembrane (TM) and four
amphipathic helices (AHs). This viral proton channel is suggested to form clusters in the …

Using molecular dynamics simulations of a coarse-grained model, in conjunction with the
weighted histogram analysis method, the adhesion modes of two spherical Janus …

This review examines the relationships between membrane chemistry, curvature-sensing
proteins, and cellular morphogenesis. Curvature-sensing proteins are often orders of …