The past decade has seen several critical advances in our understanding of hypothalamic–
pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate …

Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …

The mammalian visual system encodes information over a remarkable breadth of
spatiotemporal scales and light intensities. This performance originates with its complement …

Light around twilight provides the primary entrainment signal for circadian rhythms. Here we
review the mechanisms and responses of the mouse and human circadian systems to light …

Light exerts a wide range of effects on mammalian physiology and behavior. As well as
synchronizing circadian rhythms to the external environment, light has been shown to …

Light exerts widespread effects on physiology and behaviour. As well as the widely-
appreciated role of light in vision, light also plays a critical role in many non-visual …

The expression of defensive responses to alerting sensory cues requires both general
arousal and a specific arousal state associated with defensive emotions. However, it …

Light is known to elicit non–image-forming responses, such as effects on alertness. This has
been reported especially during light exposure at night. Nighttime results might not be …

To understand how arousal state impacts cerebral hemodynamics and neurovascular
coupling, we monitored neural activity, behavior, and hemodynamic signals in un …

An important factor in reducing variability in mouse test outcomes has been to develop
assays that can be used for continuous automated home cage assessment. Our experience …