Plant secondary metabolites as anticancer agents: successes in clinical trials and therapeutic application

AML Seca, DCGA Pinto - International journal of molecular sciences, 2018 - mdpi.com
Cancer is a multistage process resulting in an uncontrolled and abrupt division of cells and
is one of the leading causes of mortality. The cases reported and the predictions for the near …

[HTML][HTML] The impact of the BCR-ABL oncogene in the pathology and treatment of chronic myeloid leukemia

M El-Tanani, H Nsairat, II Matalka, YF Lee… - … -Research and Practice, 2024 - Elsevier
Abstract Chronic Myeloid Leukemia (CML) is characterized by chromosomal aberrations
involving the fusion of the BCR and ABL genes on chromosome 22, resulting from a …

Homoharringtonine-based induction regimen improved the Remission Rate and Survival Rate in Chinese Childhood AML: a Report from the CCLG-AML 2015 …

J Li, J Gao, A Liu, W Liu, H Xiong, C Liang… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Homoharringtonine (HHT) is commonly used for the treatment of Chinese adult
AML, and all-trans retinoic acid (ATRA) has been verified in acute promyelocytic leukemia …

Ethnopharmacology, chemodiversity, and bioactivity of Cephalotaxus medicinal plants

HAO Da-Cheng, HOU Xu-Dong, GU Xiao-Jie… - Chinese Journal of …, 2021 - Elsevier
Cephalotaxus is the only genus of Cephalotaxaceae family, and its natural resources are
declining due to habitat fragmentation, excessive exploitation and destruction. In many …

[HTML][HTML] The role of cytogenetics and molecular biology in the diagnosis, treatment and monitoring of patients with chronic myeloid leukemia

LE Dorfman, MA Floriani, TMRDR Oliveira… - Jornal Brasileiro de …, 2018 - SciELO Brasil
Chronic myeloid leukemia (CML) is the most common myeloproliferative disorder among
chronic neoplasms. The history of this disease joins with the development of cytogenetic …

Four new norlignan glycoside isomers from the twigs of Cephalotaxus oliveri Mast.

FC Meng, H Liu, XJ Huang, Y Chang, D Ren… - Tetrahedron …, 2017 - Elsevier
Four novel isomers of norlignan glycoside were isolated from Cephalotaxus oliveri Mast..
Their structures were elucidated as 3S-4 ″-O-β-d-glucopyranosylnyasol 1, 3S-4′-O-β-d …

O papel da citogenética e da biologia molecular no diagnóstico, no tratamento e no monitoramento de pacientes com leucemia mieloide crônica

LE Dorfman, MA Floriani, TMRDR Oliveira… - Jornal Brasileiro de …, 2018 - SciELO Brasil
Leucemia mieloide crônica (LMC) é a desordem mieloproliferativa mais comum entre as
neoplasias crônicas. A história dessa doença se alia ao desenvolvimento de técnicas de …

The influence of polypharmacy on nutrition

KM Piccolo, JI Boullata - … Nutrition: The Comprehensive Guide for Health …, 2015 - Springer
There is deservedly much attention being paid to malnutrition and nutrition assessment in
clinical practices. Nutrition status may be altered by many things especially in persons with …

Insight Approaches of Medicinal Plants for the Discovery of Anticancer Drugs

DCGA Pinto, AML Seca, AMS Silva - Anticancer Plants: Clinical Trials and …, 2018 - Springer
Cancer is one of the most serious illnesses of our civilization. The International Agency for
Research on Cancer estimated that 14.1 million new cancer cases were diagnosed and that …

Application of Phytodrug Delivery in Anticancer Therapy

X Wang, S Mao - Novel Drug Delivery Systems for …, 2019 - taylorfrancis.com
Cancer is a severe health menace to human beings. Chemotherapy is frequently used in
clinics. However, there are many limitations with the traditionally chemical synthetic …