The problem of wound healing in diabetes—from molecular pathways to the design of an animal model

M Mieczkowski, B Mrozikiewicz-Rakowska… - International journal of …, 2022 - mdpi.com
Chronic wounds are becoming an increasingly common clinical problem due to an aging
population and an increased incidence of diabetes, atherosclerosis, and venous …

The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis

M Khalafi, MH Sakhaei, F Kazeminasab… - Frontiers in …, 2022 - frontiersin.org
Aim We performed a systematic review and meta-analysis to investigate the effects of high-
intensity interval training (HIIT) compared with moderate-intensity continuous training (MICT) …

Diabetes pathogenesis and management: the endothelium comes of age

KM Love, EJ Barrett, SK Malin… - Journal of molecular …, 2021 - academic.oup.com
Endothelium, acting as a barrier, protects tissues against factors that provoke insulin
resistance and type 2 diabetes and itself responds to the insult of insulin resistance inducers …

Metformin may contribute to inter-individual variability for glycemic responses to exercise

SK Malin, NR Stewart - Frontiers in Endocrinology, 2020 - frontiersin.org
Metformin and exercise independently improve glycemic control. Metformin traditionally is
considered to reduce hepatic glucose production, while exercise training is thought to …

A single bout of exercise improves vascular insulin sensitivity in adults with obesity

EM Heiston, Z Liu, A Ballantyne, S Kranz, SK Malin - Obesity, 2021 - Wiley Online Library
Objective This crossover study explored the impact of a single bout of exercise on insulin‐
stimulated responses in conduit arteries and capillaries. Methods Twelve sedentary adults …

Considerations for maximizing the exercise “drug” to combat insulin resistance: role of nutrition, sleep, and alcohol

MME Remchak, KL Piersol, S Bhatti, AM Spaeth… - Nutrients, 2021 - mdpi.com
Insulin resistance is a key etiological factor in promoting not only type 2 diabetes mellitus but
also cardiovascular disease (CVD). Exercise is a first-line therapy for combating chronic …

Neural network methods for diagnosing patient conditions from cardiopulmonary exercise testing data

DE Brown, S Sharma, JA Jablonski, A Weltman - BioData Mining, 2022 - Springer
Background Cardiopulmonary exercise testing (CPET) provides a reliable and reproducible
approach to measuring fitness in patients and diagnosing their health problems. However …

Tracking Biomarker Responses to Exercise in Hypertension

E Trillaud, P Klemmer, SK Malin… - Current Hypertension …, 2023 - Springer
Abstract Purpose of Review Strong evidence is evolving that physical exercise prevents
hypertension and reduces blood pressure in patients with pre-and manifest HTN. Yet …

Nutrition interactions with exercise training on endothelial function

AJ Lobene, TJ Ragland, SL Lennon… - Exercise and sport …, 2023 - journals.lww.com
Aerobic exercise is established to raise cardiorespiratory fitness and lower obesity, type 2
diabetes (T2D), and cardiovascular disease (CVD) risk. Exercise contributes to this lower …

Addressing the continuum of Dysglycaemia and vascular complications in Prediabetes and type 2 diabetes: need for early and intensive treatment

N Ghannam, S Alahmed, R Aldahash… - Diabetes, Metabolic …, 2023 - Taylor & Francis
The onset of type 2 diabetes increases the risk of vascular complications and death. We
know now that that this risk begins long before the diabetes diagnosis. Prediabetes and type …