There are currently several different classes of drugs available for lowering cholesterol
levels. There are currently seven HMG-CoA reductase inhibitors (statins) approved for …

Lipid abnormalities beyond elevated low-density lipoprotein (LDL) cholesterol contribute to
increased risk of atherosclerotic cardiovascular disease (ASCVD) in type 2 diabetes. We …

Although hyperlipidemia is traditionally considered a risk factor for type 2 diabetes (T2D),
evidence has emerged from statin trials and candidate gene investigations suggesting that …

Background Stroke is a significant health issue in the United States, and identifying
biomarkers for the prevention and functional recovery after an acute stroke remains the …

The aim of the work is a literature review of published clinical studies on the effects of
hyperuricemia on the course of chronic heart failure (CHF). Results. High levels of uric acid …

Rapid increases in metabolic disorders, such as type 2 diabetes mellitus (T2DM) and
hyperlipidemia, are becoming a substantial challenge to worldwide public health. Traditional …

Introduction The chronic metabolic disorder diabetes mellitus is a fast-growing global
problem with huge social, health, and economic consequences, having one of the highest …

Background Apolipoprotein E (ApoE) is involved in lipid transformation and metabolism.
Although some studies have examined the association between ApoE polymorphisms and …

Purpose Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are novel drugs
that have proven efficacy in improving cardiovascular outcomes. Roles for the PCSK9 …

This paper proposes an RG hyperparameter optimization approach, based on a sequential
use of random search (R) and grid search (G), for improving the blood glucose level …