Basis of bone metabolism around dental implants during osseointegration and peri‐implant bone loss

A Insua, A Monje, HL Wang… - Journal of biomedical …, 2017 - Wiley Online Library
Despite the growing number of publications in the field of implant dentistry, there are limited
studies to date investigating the biology and metabolism of bone healing around dental …

Skeletal remodeling in health and disease

M Zaidi - Nature medicine, 2007 - nature.com
The use of genetically manipulated mouse models, gene and protein discovery and the
cataloguing of genetic mutations have each allowed us to obtain new insights into skeletal …

Blood flow controls bone vascular function and osteogenesis

SK Ramasamy, AP Kusumbe, M Schiller… - Nature …, 2016 - nature.com
While blood vessels play important roles in bone homeostasis and repair, fundamental
aspects of vascular function in the skeletal system remain poorly understood. Here we show …

Osteosarcopenic obesity: the role of bone, muscle, and fat on health

MJ Ormsbee, CM Prado, JZ Ilich, S Purcell… - Journal of cachexia …, 2014 - Springer
Osteopenia/osteoporosis, sarcopenia, and obesity are commonly observed in the process of
aging, and recent evidence suggests a potential interconnection of these syndromes with …

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.

TJ O'dell, RD Hawkins, ER Kandel… - Proceedings of the …, 1991 - National Acad Sciences
Although long-term potentiation (LTP) in the CA1 region of the hippocampus is initiated
postsynaptically by the influx of Ca2+ through N-methyl-D-aspartate receptor channels, the …

Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers

EM Hauge, D Qvesel, EF Eriksen… - Journal of bone and …, 2001 - academic.oup.com
We describe a sinus, referred to as a bone remodeling compartment (BRC), which is
intimately associated with cancellous bone remodeling. The compartment is lined on its …

Nitric oxide and bone

RJ Van'T Hof, SH Ralston - Immunology, 2001 - Wiley Online Library
Nitric oxide (NO) is a free radical which has important effects on bone cell function. The
endothelial isoform of nitric oxide synthase (eNOS) is widely expressed in bone on a …

Renal osteodystrophy

KA Hruska, SL Teitelbaum - New England Journal of Medicine, 1995 - Mass Medical Soc
Renal osteodystrophy, the term used to describe the skeletal complications of end-stage
renal disease, is a multifactorial disorder of bone remodeling. The actions of some of the …

Inhibition of nitric oxide synthase as a potential therapeutic target

AJ Hobbs, A Higgs, S Moncada - Annual review of …, 1999 - annualreviews.org
▪ Abstract Nitric oxide (NO) regulates numerous physiological processes, including
neurotransmission, smooth muscle contractility, platelet reactivity, and the cytotoxic activity of …

Bone strength: current concepts

CH Turner - Annals of the New York Academy of Sciences, 2006 - Wiley Online Library
Bones serve several mechanical functions, including acoustic amplification in the middle
ear, shielding vital organs from trauma, and serving as levers for muscles to contract against …