Abstract COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …

The COVID-19 pandemic caused much illness, many deaths, and profound disruption to
society. The production of 'safe and effective'vaccines was a key public health target. Sadly …

Animal models in SARS-CoV-2 research | Nature Methods Skip to main content Thank you for
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Summary Background Earlier Omicron subvariants including BA. 1, BA. 2, and BA. 5
emerged in waves, with a subvariant replacing the previous one every few months. More …

Background: Omicron had swept the mainland China between December 2022 and January
2023, while SARS-CoV-2 still continued to evolve. To fully prepare for the next wave, it's …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes six accessory
proteins (3a, 6, 7a, 7b, 8, and 9b) for which limited information is available on their role in …

Abstract Multiple FDA-approved SARS-CoV-2 vaccines currently provide excellent
protection against severe disease. Despite this, immunity can wane relatively fast …

ABSTRACT The Coronavirus Disease 2019 (COVID-19) pandemic continues to cause
extraordinary loss of life and economic damage. Animal models of severe acute respiratory …

We present a comprehensive analysis of SARS-CoV-2 infection and recovery using wild
type C57BL/6 mice and a mouse-adapted virus, and we demonstrate that this is an ideal …

The retransmissions of SARS-CoV-2 from several mammals–primarily mink and white-tailed
deer–to humans have raised concerns for the emergence of a new animal-derived SARS …