How does deep brain stimulation change the course of Parkinson's disease?

P Mahlknecht, T Foltynie, P Limousin… - Movement …, 2022 - Wiley Online Library
A robust body of evidence from randomized controlled trials has established the efficacy of
deep brain stimulation (DBS) in reducing off time and dyskinesias in levodopa‐treated …

Deep brain stimulation in Parkinson disease: a meta-analysis of the long-term neuropsychological outcomes

M Bucur, C Papagno - Neuropsychology review, 2023 - Springer
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus pallidum internus
(GPi) improves motor functions in patients with Parkinson's disease (PD) but may cause a …

Dietary nutrition for neurological disease therapy: Current status and future directions

XY Mao, XX Yin, QW Guan, QX Xia, N Yang… - Pharmacology & …, 2021 - Elsevier
Adequate food intake and relative abundance of dietary nutrients have undisputed effects on
the brain function. There is now substantial evidence that dietary nutrition aids in the …

Neurostimulation for advanced parkinson disease and quality of life at 5 years: a nonrandomized controlled trial

ST Jost, S Aloui, J Evans, K Ashkan… - JAMA network …, 2024 - jamanetwork.com
Importance Deep brain stimulation of the subthalamic nucleus (STN-DBS) improves quality
of life (QOL) in patients with advanced Parkinson disease (PD). However, controlled studies …

Long-term effect of apomorphine infusion in advanced Parkinson's disease: a real-life study

B Meira, B Degos, E Corsetti, M Doulazmi… - npj Parkinson's …, 2021 - nature.com
Long-term effects of continuous subcutaneous apomorphine infusion (CSAI) on health-
related quality of life (HRQoL) and predictors of CSAI discontinuation are poorly known …

Deep brain stimulation of the subthalamic nucleus in severe Parkinson's disease: relationships between dual-contact topographic setting and 1-year worsening of …

Y El Ouadih, A Marques, B Pereira, M Luisoni… - Acta …, 2023 - Springer
Background Subthalamic nucleus (STN) deep brain stimulation (DBS) alleviates severe
motor fluctuations and dyskinesia in Parkinson's disease, but may result in speech and gait …

Advantages and recent developments of autologous cell therapy for Parkinson's disease patients

TM Osborn, PJ Hallett, JM Schumacher… - Frontiers in Cellular …, 2020 - frontiersin.org
Parkinson's Disease (PD) is a progressive degenerative disease characterized by tremor,
bradykinesia, rigidity and postural instability. There are approximately 7–10 million PD …

Effects of STN-DBS on cognition and mood in young-onset Parkinson's disease: a two-year follow-up

J Hong, H Xie, Y Chen, D Liu, T Wang… - Frontiers in Aging …, 2024 - frontiersin.org
Background The effects of subthalamic nucleus deep brain stimulation (STN-DBS) on the
cognition and mood of patients with PD are still not uniformly concluded, and young-onset …

Analyses of the clinical factors and freezing of gait in association with the quality-of-life indexes in Parkinson's disease subjects with and without STN-DBS therapy

H Onder, SS Dilek, ZT Bahtiyarca… - Neurological …, 2024 - Taylor & Francis
Introduction In this research, paying particular attention to freezıng of gait (FOG), we aimed
to investigate the associations between the clinical features and quality of lilfe (QOL) …

[HTML][HTML] Nutritional neurology: Unraveling cellular mechanisms of natural supplements in brain health

S Kumar, R Malviya, S Sundram - Human Nutrition & Metabolism, 2023 - Elsevier
The consequence of appropriate food consumption and the corresponding amount of dietary
nutrients on brain function is widely recognized. More and more studies are pointing to the …