Stroke, the most prevalent cerebrovascular disease, causes serious loss of neurological
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …

Ischemic stroke is a highly complex and devastating neurological disease. The sudden loss
of blood flow to a brain region due to an ischemic insult leads to severe damage to that area …

Acute ischemic stroke is currently a major cause of disability despite improvement in
recanalization therapies. Stem cells represent a promising innovative strategy focused on …

Ischemic stroke (IS) is a serious cerebrovascular disease with high morbidity and disability
worldwide. Despite the great efforts that have been made, the prognosis of patients with IS …

Ischemic stroke remains the leading cause of death and disability, while the main
mechanisms of dominant neurological damage in stroke contain excitotoxicity, oxidative …

Neurological injuries can have numerous debilitating effects on functional status including
sensorimotor deficits, cognitive impairment, and behavioral symptoms. Despite the disease …

Background Pyroptosis is a pro-inflammatory cell death characterized by the formation of
inflammasomes. Abnormal inflammation in brain microvascular endothelial cells (BMECs) …

Background Ischemic stroke treatments are intriguing and somewhat controversial. Recent
findings have shown that human mesenchymal stem cells (MSC) may have therapeutic …

Stroke is a medical condition that results in brain injury when the blood supply to the brain is
cut off. Hemorrhagic stroke and ischemic stroke are the two primary subtypes of stroke …

Stroke is a devastating neurological disorder and one of the leading causes of mortality and
disability. To understand the cellular and molecular mechanisms of stroke and to develop …